ReviewAustralian prescriber2016
Anal fissure.
Review in Australian prescriber, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Botulinum toxin injection versus lateral internal sphincterotomy for chronic anal fissure: a meta-analysis of randomized control trials.Langenbeck's archives of surgery · 2024Pooled it
- L-Arginine is a feasible supplement to heal chronic anal fissure via reducing internal anal sphincter pressure: a randomized clinical trial study.Amino acids · 2023Trial
- Therapy and long-term outcomes of acute anal fissure: a high-volume referral centre experience with 623 patients.Techniques in coloproctology · 2026Article
- Efficacy of botulinum toxin in the treatment of chronic anal fissure: a comprehensive systematic review.Annals of medicine and surgery (2012) · 2025Article
- A Comprehensive Evidence Summary for Pain Assessment and Management After Hemorrhoidal Surgery to Inform Clinical Practice Guidelines.Journal of multidisciplinary healthcare · 2025Review
- Evaluation of the Incidence of Anal Fissures in Patients who Systemic Isotretinoin Therapy for Acne.Dermatology practical & conceptual · 2023Article
- The Effect of Topical Nifedipine versus Diltiazem on the Acute Anal Fissure: A Randomized Clinical Trial.Middle East journal of digestive diseases · 2023Article
- Topical Sucralfate for Treatment of Chronic Anal Fissure.Journal of the anus, rectum and colon · 2023Article
- Lateral Internal Anal Sphincterotomy of Chronic Anal Fissure: An Experience of 165 Cases.Cureus · 2022Article
- Benign Anorectal Disorder Management in Low-Resource Settings.Clinics in colon and rectal surgery · 2022Review
- The Effect of Baru (Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Anal fissure: diagnosis, management, and referral in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Article
- Anal fissures and liquid paraffin.Australian prescriber · 2016Article
Corrections and comments
- Commented on by
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An anal fissure is a common, mostly benign, condition that can be acute or chronic. The diagnosis is usually made on history and physical examination, but further investigations are sometimes necessary. Primary fissures are usually benign and located in the posterior or anterior position. Secondary fissures are lateral or multiple and often indicate a more serious underlying pathology. The management of primary anal fissures is generally non-operative and includes increased dietary fibre, sitz baths, topical ointments and botulinum toxin injections. If these treatments are ineffective the patient will need a surgical referral. Secondary anal fissures require further investigation. Multidisciplinary management is preferable and is essential in the case of malignancy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.