Evidence map›Paper›PMID 27041704›Full record

ReviewCurrent allergy and asthma reports2016

Food Allergy: Our Evolving Understanding of Its Pathogenesis, Prevention, and Treatment.

Onyinye I Iweala, A Wesley Burks

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Food allergy in children-the current status and the way forward.World journal of clinical pediatrics · 2022
    Review
  10. Interpreting success or failure of peanut oral immunotherapy.The Journal of clinical investigation · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. B cells and food allergy.Current opinion in pediatrics · 2021
    Review
  15. Tackling Food Allergy in Infancy.Immunology and allergy clinics of North America · 2021
    Review
  16. Article
  17. Regulation of oral antigen delivery early in life: Implications for oral tolerance and food allergy.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
    Review
  18. Article
  19. IgE-Mediated Fish Allergy in Children.Medicina (Kaunas, Lithuania) · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Onyinye I IwealaDepartment of Pediatrics, Division of Allergy, Immunology, and Rheumatology, University of North Carolina School of Medicine, 030 MacNider Hall, CB 7231, Chapel Hill, NC, 27599-7231, USA. Onyinye.Iweala@unchealth.unc.edu.
A Wesley BurksDepartment of Pediatrics, Division of Allergy, Immunology, and Rheumatology, University of North Carolina School of Medicine, 030 MacNider Hall, CB 7231, Chapel Hill, NC, 27599-7231, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergy is defined as an IgE-mediated hypersensitivity response to ingested food with allergic symptoms ranging from urticaria to life-threatening anaphylaxis. Food allergy is thought to develop because of (1) failed induction of tolerance upon initial exposure to food antigen or (2) breakdown of established tolerance to food antigen. We review current understanding of the pathogenesis, epidemiology, and natural history of food allergy, including the unconventional IgE-mediated food allergy to mammalian meat known as alpha-gal food allergy. We highlight emerging data on food allergy treatment and prevention, emphasizing the growing appeal of manipulating the gut microenvironment using probiotics and helminth products to blunt systemic allergic responses to food.

Indexed as

AnimalsFood HypersensitivityHumansImmunoglobulin EMeatMicrobiotaProbioticsImmunoglobulin EAlpha-galFood allergyHelminthMicrobiotaPeanut allergyProbiotics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.