ArticleClinical rheumatology2016
Knee pain during activities of daily living and its relationship with physical activity in patients with early and severe knee osteoarthritis.
Article in Clinical rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Health effects of a low-inflammatory diet in adults with arthritis: a systematic review and meta-analysis.Journal of nutritional science · 2020Pooled it
- Associations of Coexisting Pain and Fatigue Severity with Physical Performance and Quality of Life Among Middle-Aged and Older Individuals with Chronic Knee Pain: Secondary Analysis of a Randomized Clinical Trial.Pain medicine (Malden, Mass.) · 2021Trial
- The association between psychological characteristics and physical activity levels in people with knee osteoarthritis: a cross-sectional analysis.BMC musculoskeletal disorders · 2020Trial
- Evaluation of maslinic acid with whole-body vibration training in elderly women with knee osteoarthritis.PloS one · 2018Trial
- Three injections of freeze-dried platelet factor concentrate provide greater clinical response than single injection in the treatment of knee osteoarthritis.Journal of experimental orthopaedics · 2026Article
- Effects of Simulated Body-Mass Reduction on Peak Knee Joint Loads During Daily Functional Activities.Annals of biomedical engineering · 2026Article
- Exploring the bidirectional temporal association between daily knee pain and physical activity in people with knee osteoarthritis: An exploratory smartwatch study.Osteoarthritis and cartilage open · 2026Article
- Therapeutic outcomes of cryotherapy plus Graston Technique on pain and activities of daily living in individuals with knee pain.Frontiers in medicine · 2026Article
- Are physical activity, sleep, and joint pain associated with physical function and quality of life in individuals with multimorbidity? A cross-sectional analysis of the MOBILIZE trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- The Relationship Between Radiographic Osteoarthritis, Step Counts, and Pain Levels in Patients Undergoing Hip and Knee Arthroplasty.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- A Task-Agnostic Knee Exoskeleton for Reducing Osteoarthritis Pain Across Activities of Daily Life: A Pilot Study.IEEE ... International Conference on Rehabilitation Robotics : [proceedings] · 2025Article
- Deep Learning for Automatic Knee Osteoarthritis Severity Grading and Classification.Indian journal of orthopaedics · 2024Article
- Stair-Climbing Training with Interferential Electrotherapy Improves Knee Muscle Strength, Dynamic Postural Stability, Pain Score, and Physical Activity in Patients with Knee Osteoarthritis.Diagnostics (Basel, Switzerland) · 2024Article
- Dynamics of the suprapatellar bursa during knee joint extension.Surgical and radiologic anatomy : SRA · 2024Article
- Associations of pain sensitivity and conditioned pain modulation with physical activity: findings from the Multicenter Osteoarthritis Study (MOST).Osteoarthritis and cartilage · 2024Observational
- Factors associated with physical activity following total knee arthroplasty for knee osteoarthritis: a longitudinal study.BMC musculoskeletal disorders · 2024Article
- Improvement in Gait Speed Affects Short-term Improvement in Activities of Daily Living in Patients with Moderate and Severe Knee Osteoarthritis.Progress in rehabilitation medicine · 2024Article
- The relationship between experience of knee pain and physical activity participation: A scoping review of quantitative studies.International journal of nursing sciences · 2023Article
- Effects of low-intensity pulsed ultrasound on the infrapatellar fat pad in knee osteoarthritis: a randomized, double blind, placebo-controlled trial.Journal of physical therapy science · 2023Article
- Early Osteoarthritis Questionnaire (EOAQ): a tool to assess knee osteoarthritis at initial stage.Therapeutic advances in musculoskeletal disease · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate whether knee pain during various activities of daily living (ADLs) is associated with physical activity in patients with early and severe knee osteoarthritis (OA). We hypothesized that the painful ADLs associated with decreased physical activity differ according to disease severity. This cross-sectional study enrolled 270 patients with medial knee OA, assigned to either the early (Kellgren Lawrence [K/L] grade 1-2) or the severe group (K/L grade 3-4). Physical activity was assessed using a pedometer. Knee pain during six ADLs (waking up in the morning, walking on a flat surface, ascending stairs, etc.) was evaluated using a questionnaire. We performed multiple regression and quantile regression analysis to investigate whether knee pain during each ADL was associated with physical activity. In the early group, the more knee pain they experienced while ascending stairs, the lower their physical activity was (75th regression coefficient = -1033.70, P = 0.018). In the severe group, the more knee pain they experienced while walking on a flat surface or bending to the floor or standing up, the lower their physical activity was (unstandardized coefficients = -1850.87, P = 0.026; unstandardized coefficients = -2640.35, P = 0.010). Knee pain while ascending stairs and while walking on a flat surface or bending to the floor or standing up was a probable limiting factor for physical activity in early and severe knee OA, respectively. These findings suggested that a reduction in task-specific knee pain according to disease severity could improve physical activity levels.
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Registered trials
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