Evidence map›Paper›PMID 2704080›Full record

ArticleJournal of virology1989

The Mlvi-1 locus involved in the induction of rat T-cell lymphomas and the pvt-1/Mis-1 locus are identical.

C F Koehne, P A Lazo, K Alves, J S Lee, P N Tsichlis, P V O'Donnell

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Evolutionarily new sequences expressed in tumors.Infectious agents and cancer · 2006
    Article
  3. Article
  4. Article
  5. Article
  6. The Myb and Ahi-1 genes are physically very closely linked on mouse chromosome 10.Mammalian genome : official journal of the International Mammalian Genome Society · 1994
    Article
  7. A rat genetic linkage map and comparative maps for mouse or human homologous rat genes.Mammalian genome : official journal of the International Mammalian Genome Society · 1994
    Article
  8. Article
  9. Mouse chromosome 15.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  10. Article
  11. Mouse chromosome 15.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Review
  12. Article
  13. Pvt-1 transcripts are found in normal tissues and are altered by reciprocal(6;15) translocations in mouse plasmacytomas.Proceedings of the National Academy of Sciences of the United States of America · 1990
    Article
  14. Article
  15. Article
  16. Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi-1 or Mlvi-4 in rat T-cell lymphomas.Proceedings of the National Academy of Sciences of the United States of America · 1990
    Article
  17. Activation of the Mlvi-1/mis1/pvt-1 locus in Moloney murine leukemia virus-induced T-cell lymphomas.Proceedings of the National Academy of Sciences of the United States of America · 1989
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

C F KoehneMemorial Sloan-Kettering Cancer Center, New York, New York 10021.
P A Lazo
K Alves
J S Lee
P N Tsichlis
P V O'Donnell
Memorial Sloan Kettering Cancer Center · US

Funding

DNA REARRANGEMENTS IN MOMULV-INDUCED THYMOMASR01CA038047 · NCI · THOMAS JEFFERSON UNIVERSITY · PI TSICHLIS, PHILIP N · 1986 to 2000
$328k
MECHANISMS OF ACTION OF VIRAL &NON-VIRAL ONCOGENESP01CA016599 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI HAYWARD, WILLIAM S · 1985 to 1993
–
KINETIC STUDY OF VIRUS-ACCELERATED LEUKEMIAR01CA031491 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI HAYWARD, WILLIAM S · 1985 to 1988
–
NCI NIH HHS CA-16599NCI NIH HHS CA-31491NCI NIH HHS CA-38047
6 · The paper itself

Abstract

Mlvi-1 defines a locus of proviral integration in rat thymomas induced by Moloney murine leukemia virus. pvt-1/Mis-1 represents an independently identified locus which becomes rearranged either by chromosomal translocation in murine plasmacytomas or by provirus insertion in retrovirus-induced murine and rat thymic lymphomas. Although it had been claimed that pvt-1/Mis-1 and Mlvi-1 represent two different loci, we present here evidence showing that they are identical. This finding demonstrates the need for rigorous characterization of any newly identified common regions of integration in retrovirus-induced neoplasms.

Indexed as

Cell Transformation, ViralRegulatory Sequences, Nucleic AcidAnimalsBlotting, SouthernChromosome MappingDNA ProbesLymphomaMiceMoloney murine leukemia virusRatsRestriction MappingThymomaDNA Probes

Identifiers

PMID2704080
PMCPMC250659
OpenAlexW2106734593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.