ArticleJournal of biomechanics2016
Study of cardiovascular function using a coupled left ventricle and systemic circulation model.
Article in Journal of biomechanics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Simulating impaired left ventricular-arterial coupling in aging and disease: a systematic review.Biomedical engineering online · 2024Pooled it
- Patient-Specific Analysis of Ventricular Vortex Formation and Flow Energetics in Rheumatic and Calcific Mitral Stenosis.Annals of biomedical engineering · 2026Article
- Composite B-spline regularized delta functions for the immersed boundary method: Divergence-free interpolation and gradient-preserving force spreading.Journal of computational physics · 2026Article
- A numerical framework for preprocedural prosthetic valve positioning and hemodynamic evaluation.Biomechanics and modeling in mechanobiology · 2025Article
- LOCAL DIVERGENCE-FREE IMMERSED FINITE ELEMENT-DIFFERENCE METHOD USING COMPOSITE B-SPLINES.Advances in computational science and engineering · 2025Article
- Benchmarking the Immersed Boundary Method for Viscoelastic Flows.Journal of computational physics · 2024Article
- An Image-Based Computational Fluid Dynamics Study of Mitral Regurgitation in Presence of Prolapse.Cardiovascular engineering and technology · 2023Article
- A fast computational model for circulatory dynamics: effects of left ventricle-aorta coupling.Biomechanics and modeling in mechanobiology · 2023Article
- On the Lagrangian-Eulerian Coupling in the Immersed Finite Element/Difference Method.Journal of computational physics · 2022Article
- Self-Similar Functional Circuit Models of Arteries and Deterministic Fractal Operators: Theoretical Revelation for Biomimetic Materials.International journal of molecular sciences · 2021Article
- Fluid-structure interaction in a fully coupled three-dimensional mitral-atrium-pulmonary model.Biomechanics and modeling in mechanobiology · 2021Article
- Personalized intervention cardiology with transcatheter aortic valve replacement made possible with a non-invasive monitoring and diagnostic framework.Scientific reports · 2021Article
- The Comparison of Different Constitutive Laws and Fiber Architectures for the Aortic Valve on Fluid-Structure Interaction Simulation.Frontiers in physiology · 2021Article
- Heart-Lung Interactions During Mechanical Ventilation: Analysis via a Cardiopulmonary Simulation Model.IEEE open journal of engineering in medicine and biology · 2021Article
- Effect of myofibre architecture on ventricular pump function by using a neonatal porcine heart model: from DT-MRI to rule-based methods.Royal Society open science · 2020Article
- An Immersed Interface Method for Discrete Surfaces.Journal of computational physics · 2020Article
- A review on low-dimensional physics-based models of systemic arteries: application to estimation of central aortic pressure.Biomedical engineering online · 2019Review
- In-silico assessment of the effects of right ventricular assist device on pulmonary arterial hypertension using an image based biventricular modeling framework.Mechanics research communications · 2019Article
- Finite state machine implementation for left ventricle modeling and control.Biomedical engineering online · 2019Article
- A One-Dimensional Hemodynamic Model of the Coronary Arterial Tree.Frontiers in physiology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
To gain insight into cardio-arterial interactions, a coupled left ventricle-systemic artery (LV-SA) model is developed that incorporates a three-dimensional finite-strain left ventricle (LV), and a physiologically-based one-dimensional model for the systemic arteries (SA). The coupling of the LV model and the SA model is achieved by matching the pressure and the flow rate at the aortic root, i.e. the SA model feeds back the pressure as a boundary condition to the LV model, and the aortic flow rate from the LV model is used as the input for the SA model. The governing equations of the coupled system are solved using a combined immersed-boundary finite-element (IB/FE) method and a Lax-Wendroff scheme. A baseline case using physiological measurements of healthy subjects, and four exemplar cases based on different physiological and pathological scenarios are studied using the LV-SA model. The results of the baseline case agree well with published experimental data. The four exemplar cases predict varied pathological responses of the cardiovascular system, which are also supported by clinical observations. The new model can be used to gain insight into cardio-arterial interactions across a range of clinical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.