ArticleBMC health services research2016
Potentially inappropriate medication in the elderly in Germany: an economic appraisal of the PRISCUS list.
Article in BMC health services research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Potential inappropriate medications and drug-drug interactions in adverse drug reactions in the elderly: a retrospective study in a pharmacovigilance database.Frontiers in pharmacology · 2025Article
- Can peer effects explain prescribing appropriateness? a social network analysis.BMC medical research methodology · 2023Article
- Potentially inappropriate medication including drug-drug interaction and the risk of frequent falling, hospital admission, and death in older adults - results of a large cohort study (getABI).Frontiers in pharmacology · 2023Article
- Extended Pharmacist Assessment of Medication Safety for Nursing Home Residents-A Cross-Sectional and Prospective Study.Journal of clinical medicine · 2022Article
- Preoperative medication use and development of postoperative delirium and cognitive dysfunction.Clinical and translational science · 2021Observational
- Fall-risk-increasing adverse reactions-is there value in easily accessible drug information? A case-control study.European journal of clinical pharmacology · 2019Article
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Authors and funding
5 authors.
Funding
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Abstract
backgroundSeveral lists of potentially inappropriate medication (PIM) for elderly patients have been developed worldwide in recent years. Those lists intend to reduce prescriptions of drugs that carry an unnecessarily high risk of adverse drug events in elderly patients. In 2010, an expert panel published the PRISCUS list for the German drug market. This study calculates the amount of drug reimbursement for PIM in Germany and potential cost effects from the perspective of statutory health insurance when these are replaced by the substitutes recommended by the PRISCUS list.
methodsRegister-based data for the 30 top-selling drugs on the PRISCUS list in 2009 for patients greater than or equal to 65 years of age were provided by the Scientific Institute of the German Local Health Care Fund. We calculated the percentage of sales and defined daily doses for patients greater than or equal to 65 years of age compared with the total statutory health insurance population. Reimbursement costs for the recommended substitutions were estimated by considering different scenarios.
resultsIn 2009, drug reimbursement for the 30 top-selling PIM prescribed to patients greater than or equal to 65 years of age were calculated to be €305.7 million. Prescribing the recommended substitution medication instead of PIM would lead to an increased total reimbursement cost for the German health care system ranging between from €325.9 million to €810.0 million.
conclusionsThe results show that the substitution of PIM by medication deemed to be more appropriate for the elderly comes along with additional costs. Consequently, there is no short-term incentive for doing so from a payer perspective. Future studies have to consider the long-term effects and other sectors.
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