ArticleMycopathologia2016
Spondylodiscitis Due to Aspergillus terreus in an Immunocompetent Host: Case Report and Literature Review.
Article in Mycopathologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Aspergillus spp. osteoarticular infections: an updated systematic review on the diagnosis, treatment and outcomes of 186 confirmed cases.Medical mycology · 2022Pooled it
- Lumbar postoperativeFrontiers in medicine · 2026Article
- Article
- Successful Management of Spondylodiscitis Caused byJournal of fungi (Basel, Switzerland) · 2025Article
- Metagenomic next-generation sequencing enabled diagnosis ofFrontiers in medicine · 2025Article
- An immunocompetent host with blood-disseminatedThe Journal of international medical research · 2024Review
- Review
- Individualized Pharmaceutical Care for Antifungal Therapy in a Patient withInfection and drug resistance · 2023Article
- Successful treatment of vertebral osteomyelitis due toBMJ case reports · 2022Article
- Isavuconazole in the Treatment ofAntibiotics (Basel, Switzerland) · 2022Review
- Spondylodiscitis Caused byDiagnostics (Basel, Switzerland) · 2021Review
- Spontaneous Vertebral Aspergillosis, the State of Art: A Systematic Literature Review.Neurospine · 2021Article
- Aspergillus spondylitis: case series and literature review.BMC musculoskeletal disorders · 2020Review
- Aspergillus terreus spondylodiscitis following an abdominal stab wound: a case report.Journal of medical case reports · 2019Article
- The Curious Case of "Case Report" of Infections Caused by Human and Animal Fungal Pathogens: An Educational Tool, an Online Archive, or a Format in Need of Retooling.Mycopathologia · 2018Article
- Quantitative B-lymphocyte deficiency and increased TCRγδ T-lymphocytes in acute infectious spondylodiscitis.Scientific reports · 2018Observational
- InvasiveInfection and drug resistance · 2017Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspergillus terreus, a saprophytic fungus, is recognized as an emerging pathogen responsible for various infections in human beings. However, bone and joint involvement is uncommon. We report a rare case of A. terreus spondylodiscitis in a 20-year-old male with a past history of recurrent, incompletely treated pulmonary tuberculosis. Clinical signs at the time of admission included cough, low-grade fever, general weakness and left-sided back pain. Histological examination of spinal biopsy samples revealed lesions of necrosis, granulomatous inflammation and septate hyphae with acute-angle branching. A. terreus was recovered from culture. The patient received antifungal therapy with voriconazole plus caspofungin and underwent surgical debridement. Further investigations revealed no cause of primary immunodeficiency such as chronic granulomatous disease, severe combined immunodeficiency syndrome or disorders of the IL-12/IFNγ signaling pathway. Moreover, HIV serological tests resulted negative and the patient was not under immunosuppressive therapy. Unfortunately, owing to precarity and medication non-adherence, vertebral sequelae occurred. This new report emphasizes the need to consider a fungal infection in patients with spondylodiscitis, regardless of the immune status.
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