Trial reportBMC musculoskeletal disorders2016
Effectiveness of a telemonitoring intensive strategy in early rheumatoid arthritis: comparison with the conventional management approach.
Trial report in BMC musculoskeletal disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Randomized controlled trials of digital health interventions for rheumatic disease management: a systematic review.Bulletin of the World Health Organization · 2025Pooled it
- Pooled it
- Pooled it
- Tele-health interventions to support self-management in adults with rheumatoid arthritis: a systematic review.Rheumatology international · 2021Pooled it
- Smartphone-Assisted Patient-Initiated Care Versus Usual Care in Patients With Rheumatoid Arthritis and Low Disease Activity: A Randomized Controlled Trial.Arthritis & rheumatology (Hoboken, N.J.) · 2022Trial
- Exploring digital health technology in rheumatology: a scoping review on benefits, challenges, and future possibilities.EULAR rheumatology open · 2026Review
- Digital Health Intervention for Patient Monitoring in Immune-Mediated Inflammatory Diseases: Cocreation and Feasibility Study of the IMIDoc Platform.JMIR human factors · 2025Article
- Patient-reported outcomes as early warning signs of flare following drug cessation in rheumatoid arthritis.RMD open · 2025Article
- Article
- Clinical implications of teleradiology in rheumatic and musculoskeletal diseases: improving rheumatic care.Rheumatology international · 2025Review
- Early detection of rheumatoid arthritis through patient empowerment by tailored digital monitoring and education: a feasibility study.Rheumatology international · 2025Article
- Rheumatology in the digital health era: status quo and quo vadis?Nature reviews. Rheumatology · 2024Review
- Remote monitoring of patients with rheumatoid arthritis in a low disease activity state: a mixed methods evaluation across six hospitals in London, UK.Rheumatology (Oxford, England) · 2024Article
- Toward Telemonitoring in Immune-Mediated Inflammatory Diseases: Protocol for a Mixed Attention Model Study.JMIR research protocols · 2024Article
- Recommendation to implementation of remote patient monitoring in rheumatology: lessons learned and barriers to take.RMD open · 2023Article
- Telemedicine in Rheumatoid Arthritis: A Review of the PubMed Literature.Mediterranean journal of rheumatology · 2023Review
- Future challenges in rheumatology - is telemedicine the solution?Therapeutic advances in musculoskeletal disease · 2022Review
- [Telemedical care and IT-based systems in rheumatology].Zeitschrift fur Rheumatologie · 2021Review
- Acceptance of Telerheumatology by Rheumatologists and General Practitioners in Germany: Nationwide Cross-sectional Survey Study.Journal of medical Internet research · 2021Article
- Telemedicine for patients with rheumatic and musculoskeletal diseases during the COVID-19 pandemic; a positive experience in the Netherlands.Rheumatology international · 2021Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe advent of Internet and World Wide Web has created new perspectives toward interaction between patients and healthcare professionals. Telemonitoring patients with rheumatoid arthritis (RA) is an emerging concept to guide the collaborative management treatment and improve outcomes in patients. The objective of this study was to investigate whether an intensive treatment strategy, according to a telemonitoring protocol, is more effective than conventional management strategy in reaching remission and comprehensive disease control (CDC) after 1 year in early rheumatoid arthritis (ERA) patients.
methodsForty-four ERA patients were randomly allocated into two groups: the telemonitoring intensive strategy (TIS) group (group 1) or the conventional strategy (CS) group (group 2). Three patients refused to participate. In group 1 (n = 21), a remote monitoring system of disease activity, in combination with protocolised treatment adjustments aiming for remission was applied. In group 2 (n = 20), patients were treated according to daily clinical practice, with regular evaluation of disease activity, but without protocolised treatment adjustments. A telemedical care called "REmote TElemonitoring for MAnaging Rheumatologic Condition and HEaltcare programmes" (RETE-MARCHE), was developed to perform the remote monitoring.
resultsA higher percentage of patients in the TIS group achieved CDAI remission vs patients in the CS group (38.1 % vs 25 % at year 1, p <0.01). Time to achieve remission was significantly shorter in the group 1 than in the group 2, with a median of 20 weeks vs a median over 36-weeks (p <0.001). Concordantly, the patients in group 1 showed a greater improvement (p <0.001), compared with group 2 in terms of functional impairment (71.4 % vs 35 %) and radiological damage progression (23.8 % vs 10 %), resulting in a greater rate of CDC (19.4 % vs 5 %).
conclusionsAccording to our results, an intensive treatment strategy by telemonitoring leads to more effective disease remission and more rapid CDC than treatment according to conventional management strategy in ERA.
trial registrationTRIAL REGISTRATION NUMBER: ISRCTN13142685 Date of registration: March, 17(th) 2016.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.