ArticleBMC geriatrics2016
The impact of preventive measures on the burden of femoral fractures - a modelling approach to estimating the impact of fall prevention exercises and oral bisphosphonate treatment for the years 2014 and 2025.
Article in BMC geriatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Effectiveness of dance interventions for falls prevention in older adults: systematic review and meta-analysis.Age and ageing · 2024Pooled it
- Health-Economic Evaluation of the German Osteoporotic Fracture Prevention Program in Rural Areas (OFRA): Mobility and Falls Prevention Classes, Examination of Bone Health, and Consultation on Safety in the Living Environment.Journal of general internal medicine · 2023Trial
- Effect of an osteoporotic fracture prevention program on fracture incidence in routine care: a cluster-randomized trial.BMC medicine · 2022Trial
- The osteoporotic fracture prevention program in rural areas (OFRA): a protocol for a cluster-randomized health care fund driven intervention in a routine health care setting.BMC musculoskeletal disorders · 2016Trial
- App-assisted rehabilitation concept for geriatric patients after proximal femur fractures (PROGRES(S)): a qualitative study.BMC geriatrics · 2026Article
- The development, incidence and treatment trends of trochanteric fractures in Germany: a cohort study.Journal of orthopaedic surgery and research · 2023Article
- Single-stage total hip arthroplasty after failed fixation of proximal femoral fractures: an increased risk for periprosthetic joint infections?Archives of orthopaedic and trauma surgery · 2022Article
- Patient-specific risk factors for adverse outcomes following geriatric proximal femur fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Review
- Smartphone Apps to Support Falls Rehabilitation Exercise: App Development and Usability and Acceptability Study.JMIR mHealth and uHealth · 2020Article
- Epidemiology of hip fractures : Systematic literature review of German data and an overview of the international literature.Zeitschrift fur Gerontologie und Geriatrie · 2019Review
- [Trochanteric and subtrochanteric fractures].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDue to the demographic transition with a growing number of old and oldest-old persons the absolute number of fragility fractures is expected to increase in industrialized countries unless effective preventive efforts are intensified. The main causes leading to fractures are osteoporosis and falls. The aim of this study is to develop population based models of the potential impact of fall-prevention exercise and oral bisphosphonates over the coming decade.
methodsThe German federal state of Bavaria served as the model population. Model interventions were limited to community-dwelling persons aged 65 years and older. Models are based on fall-prevention exercise being offered to all persons aged 70 to 89 years and oral bisphosphonate treatment offered to all persons with osteoporosis as defined by a T-score of ≤ - 2.5. Treatment effect sizes are estimated from meta-analyses. Reduction in all femoral fractures in the population of community-dwelling persons aged 65 years and older is the outcome of interest. A spreadsheet-based modelling approach was used for prediction.
resultsIn 2014, reduction of femoral fractures by 10 % required 21 % of all community-dwelling persons aged 70-89 to participate in fall-prevention exercise, or 37 % of those with osteoporosis to receive oral bisphosphonates. Without intervention, demographic changes will result in a 24 % increase in femoral fractures by 2025. To lower the increase of fractures between 2014 and 2025 to 10 %, fall-prevention-exercise participation rate needs to be 25 % and bisphosphonate treatment rates 41 %, whereas to hold the 2025 rates flat at 2014 rates require 43 % fall-prevention-exercises participation, and is not achievable using oral bisphosphonates.
conclusionsUnrealistic high treatment and participation rates of the two analysed measures are needed to achieve substantial effects on the expected burden of femoral fractures at present and in the future.
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