ReviewDigestive diseases and sciences2016
Spontaneous Regression of Hepatocellular Carcinoma with Multiple Lung Metastases: A Case Report and Review of the Literature.
Review in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Occult Thyroid Carcinoma Localized to Three Cervical Lymph Nodes Without Primary Origin in the Thyroid Gland: A Case Report.Case reports in endocrinology · 2026Article
- Spontaneous regression of hepatocellular carcinoma after alcohol and smoking abstinence and bone fracture surgery: A case report.Medicine · 2025Article
- Complete regression of intrahepatic cholangiocarcinoma after right portal vein ligation. Case report.International journal of surgery case reports · 2024Article
- Article
- Spontaneous regression of metastatic hepatocellular carcinoma following 3 weeks of lenvatinib.BMJ case reports · 2022Article
- Understanding the Immunoenvironment of Primary Liver Cancer: A Histopathology Perspective.Journal of hepatocellular carcinoma · 2022Review
- Spontaneous regression of lung metastases after transarterial chemoembolization for hepatocellular carcinoma.Radiology case reports · 2021Article
- Cordycepin suppresses the migration and invasion of human liver cancer cells by downregulating the expression of CXCR4.International journal of molecular medicine · 2020Article
- Spontaneous regression of pancreatic cancer with liver metastases.BMJ case reports · 2019Article
- Spontaneous regression of colorectal liver metastasis.Clinical journal of gastroenterology · 2018Article
- Tumor reductive therapies and antitumor immunity.Oncotarget · 2017Review
- Metastatic thyroid carcinoma without identifiable primary tumor within the thyroid gland: a retrospective study of a rare phenomenon.Human pathology · 2017Article
- Spontaneous regression of hepatocellular carcinoma: A mini-review.World journal of gastroenterology · 2017Review
- Spontaneous Regression of Advanced Hepatocellular Carcinoma.Case reports in gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spontaneous regression of hepatocellular carcinoma (HCC) is a rare event. Here we present a case of spontaneous regression of metastatic HCC. A 53-year-old man with hepatitis C and alcoholic cirrhosis was found to have a large liver mass consistent with HCC based on its radiographic features. Imaging also revealed left portal and hepatic vein thrombosis, as well as multiple lung nodules concerning for metastases. Approximately 2 months after the initial diagnosis, both the primary liver lesion and the lung metastases decreased in size and eventually resolved without any intervention. Thereafter, the left hepatic vein thrombus progressed into the inferior vena cava and the right atrium, and the patient died due to right heart failure. In this case report and literature review, we discuss the potential mechanisms for and review the literature on spontaneous regression of metastatic HCC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.