ArticleEating and weight disorders : EWD2017
Plasma orexin-A level associated with physical activity in obese people.
Article in Eating and weight disorders : EWD, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Plasma orexin A levels in recently menopausal women during and 3 years following use of hormone therapy.Maturitas · 2017Trial
- The orexin system as a pharmacological target in inflammation: peripheral mechanisms and safety implications.Frontiers in pharmacology · 2026Review
- Orexin and Lifestyle Habits: A Meaningful Connection Among Nutrition, Physical Activity, and Sleep Pattern in Health and Diseases.International journal of molecular sciences · 2025Review
- Potential role of Amyloid-β on the association between Orexin-A and blood-brain barrier leakage of globus pallidus in Alzheimer's disease and dementia with lewy bodies.Alzheimer's research & therapy · 2025Article
- Interactions between Lateral Hypothalamic Orexin and Dorsal Raphe Circuitry in Energy Balance.Brain sciences · 2024Article
- Physiological Role of Orexin/Hypocretin in the Human Body in Motivated Behavior: A Comprehensive Review.Cureus · 2023Review
- Physiological Role of Orexinergic System for Health.International journal of environmental research and public health · 2022Review
- Trends in spontaneous physical activity and energy expenditure among adults in a respiratory chamber, 1985 to 2005.Obesity (Silver Spring, Md.) · 2022Article
- Orexin, serotonin, and energy balance.WIREs mechanisms of disease · 2022Review
- Subcutaneous Adipose Tissue Browning, Serum Orexin-A, and Insulin Resistance Following Aerobic Exercise in High-Fat Diet Obesity Male Wistar Rats.International journal of preventive medicine · 2021Article
- The Important Role of Adiponectin and Orexin-A, Two Key Proteins Improving Healthy Status: Focus on Physical Activity.Frontiers in physiology · 2020Review
- Physical activity in depressed and non-depressed patients with obesity.Eating and weight disorders : EWD · 2018Article
- Sympathetic, Metabolic Adaptations, and Oxidative Stress in Autism Spectrum Disorders: How Far From Physiology?Frontiers in physiology · 2018Article
- Spontaneous Physical Activity Defends Against Obesity.Current obesity reports · 2017Review
- Impact of Orexin-A Treatment on Food Intake, Energy Metabolism and Body Weight in Mice.PloS one · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo measure the amount of physical activity (PA) among obese adults, investigate the association between plasma orexin-A level and PA patterns, and explore the effect of orexin on the prevention and control of obesity.
methodsInterviews were conducted in 218 participants (106 obese; 73 overweight; and 39 normal) who ranged in age between 18 and 70 years using a survey that included sociodemographic variables. The International Physical Activity Questionnaire (IPAQ-long version) was used to measure PA. A total of 178 participants agreed to submit blood sample collections, and plasma orexin-A content was measured by ELISA testing.
resultsThe average level of orexin-A was 85.34 ± 42.85 ng/L in the obese group, 97.38 ± 36.72 ng/L in the overweight group, and 106.56 ± 52.09 ng/L in the control group, which was significantly different (P = 0.03). The concentration of plasma orexin-A correlated with the total PA (P = 0.000), moderate PA (obese = 0.007; overweight: P = 0.000; control: P = 0.000), and walking PA (P = 0.000) in all three groups. Working and domestic PAs were significantly associated with the plasma orexin-A level (P < 0.0001).
conclusionsThe plasma orexin-A level was associated with PA in obese and overweight people, including many aspects of daily life, such as working, domestic work, and walking especially.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.