Evidence map›Paper›PMID 27037707›Full record

Observational studyEuropean child & adolescent psychiatry2016

The impact of ADHD on the health and well-being of ADHD children and their siblings.

Tessa Peasgood, Anupam Bhardwaj, Katie Biggs, John E Brazier, David Coghill, Cindy L Cooper, David Daley, Cyril De Silva, Val Harpin, Paul Hodgkins and 3 more

Registry-linked trialOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in European child & adolescent psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06971640 (Advancing Identification of Circadian Delay in ADHD Youth), which is not on this map. Cited by 61 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 9 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06971640 recruitingnot on this mapstarted 2025, after this paper: background citation

Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition

TypeobservationalSponsorDuke UniversityRan2025 to 2029Enrolled250ConditionsADHD - Attention Deficit Disorder With Hyperactivity, ADHD
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 9 syntheses or guidelines pooled it, 151 citations in OpenAlex.

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  6. A systematic review of health state utility values and psychometric performance of generic preference-based instruments for children and adolescents with mental health problems.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
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  18. Sphingolipids in Emotional Well-Being.Journal of neurochemistry · 2026
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Tessa PeasgoodSchool of Health and Related Research (ScHARR), Regent Court, 30 Regent Street, Sheffield, S1 4DA, UK.
Anupam BhardwajNorth East London Foundation Trust and University College of London, London, UK.
Katie BiggsSchool of Health and Related Research (ScHARR), Regent Court, 30 Regent Street, Sheffield, S1 4DA, UK. c.e.biggs@sheffield.ac.uk.
John E BrazierSchool of Health and Related Research (ScHARR), Regent Court, 30 Regent Street, Sheffield, S1 4DA, UK.
David CoghillThe Department of Psychiatry, The University of Dundee, Dundee, UK.
Cindy L CooperSchool of Health and Related Research (ScHARR), Regent Court, 30 Regent Street, Sheffield, S1 4DA, UK.
David DaleyDivision of Psychiatry & Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK.
Cyril De SilvaMedway NHS Foundation Trust, Kent, UK.
Val HarpinSheffield Children's NHS Foundation Trust, Sheffield, UK.
Paul HodgkinsGlobal HEOR and Epidemiology, Shire, 725 Chesterbrook Boulevard, Wayne, PA 19087, USA.
Amulya NadkarniLincolnshire Partnership NHS Foundation Trust, Lincolnshire, UK.
Juliana SetyawanGlobal HEOR and Epidemiology, Shire, 725 Chesterbrook Boulevard, Wayne, PA 19087, USA.
Edmund J S Sonuga-BarkeDepartment of Psychology, University of Southampton, Southampton, UK.
Takeda (United States) · USLincolnshire Partnership NHS Foundation Trust · GBMedway NHS Foundation Trust · GBNorth East London NHS Foundation Trust · GBSheffield Children's NHS Foundation Trust · GBUniversity of Dundee · GBUniversity of Nottingham · GBUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood attention-deficit/hyperactivity disorder (ADHD) has been associated with reduced health and well-being of patients and their families. The authors undertook a large UK survey-based observational study of the burden associated with childhood ADHD. The impact of ADHD on both the patient (N = 476) and their siblings (N = 337) on health-related quality of life (HRQoL) and happiness was quantified using multiple standard measures [e.g. child health utility-9D (CHU-9D), EuroQol-5D-Youth]. In the analysis, careful statistical adjustments were made to ensure a like-for-like comparison of ADHD families with two different control groups. We controlled for carers' ADHD symptoms, their employment and relationship status and siblings' ADHD symptoms. ADHD was associated with a significant deficit in the patient's HRQoL (with a CHU-9D score of around 6 % lower). Children with ADHD also have less sleep and were less happy with their family and their lives overall. No consistent decrement to the HRQoL of the siblings was identified across the models, except that related to their own conduct problems. The siblings do, however, report lower happiness with life overall and with their family, even when controlling for the siblings own ADHD symptoms. We also find evidence of elevated bullying between siblings in families with a child with ADHD. Overall, the current results suggest that the reduction in quality of life caused by ADHD is experienced both by the child with ADHD and their siblings.

Indexed as

Cost of IllnessAdolescentAttention Deficit Disorder with HyperactivityChildCross-Sectional StudiesFemaleHumansMaleQuality of LifeSiblingsADHDBurdenChildrenCHU-9DEQ-5D-YHealth-related quality of lifeImpact of ADHD on family outcomesLife satisfactionSiblingsSleepUtilityWell-being

Identifiers

PMID27037707
PMCPMC5083759
OpenAlexW2333413009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.