ArticleThe Journal of infectious diseases2016
Varicella Zoster Virus Infection in Granulomatous Arteritis of the Aorta.
Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- Article
- Takayasu Arteritis Following Necrotizing Fasciitis: A Case Report and Brief Review of the Literature.Cureus · 2025Article
- Giant Cell Arteritis: Advances in Understanding Pathogenesis and Implications for Clinical Practice.Cells · 2024Review
- Case Report: Superior mesenteric artery vasculitis causing aneurysm following COVID-19 infection.Frontiers in surgery · 2024Article
- Systemic lupus erythematosus with visceral varicella: A case report.World journal of clinical cases · 2022Article
- Targeted RNA Sequencing of Formalin-Fixed, Paraffin-Embedded Temporal Arteries From Giant Cell Arteritis Cases Reveals Viral Signatures.Neurology(R) neuroimmunology & neuroinflammation · 2021Article
- The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.PLoS pathogens · 2021Article
- A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation.Nature communications · 2020Article
- Central nervous system infections produced by varicella zoster virus.Current opinion in infectious diseases · 2020Review
- The microbiome in autoimmune rheumatic disease.Best practice & research. Clinical rheumatology · 2020Review
- Varicella Zoster Virus Alters Expression of Cell Adhesion Proteins in Human Perineurial Cells via Interleukin 6.The Journal of infectious diseases · 2019Article
- Successful management of visceral disseminated varicella zoster virus infection during treatment of membranous nephropathy: a case report.BMC infectious diseases · 2019Article
- Varicella Zoster Virus in Giant Cell Arteritis: A Review of Current Medical Literature.Neuro-ophthalmology (Aeolus Press) · 2019Review
- Disseminated zoster in an adult patient with extensive burns: a case report.Virology journal · 2019Article
- Varicella Zoster Virus Vasculopathy.The Journal of infectious diseases · 2018Article
- Herpes Zoster as a Risk Factor for Incident Giant Cell Arteritis.Arthritis & rheumatology (Hoboken, N.J.) · 2017Article
- Varicella zoster virus vasculopathy: The expanding clinical spectrum and pathogenesis.Journal of neuroimmunology · 2017Review
- Is chickenpox so bad, what do we know about immunity to varicella zoster virus, and what does it tell us about the future?The Journal of infection · 2017Review
- Update on the management of giant cell arteritis.Therapeutic advances in chronic disease · 2017Review
- Varicella Zoster Virus and Large Vessel Vasculitis, the Absence of an Association.Pathogens & immunity · 2017Article
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
Granulomatous arteritis characterizes the pathology of giant cell arteritis, granulomatous aortitis, and intracerebral varicella zoster virus (VZV) vasculopathy. Because intracerebral VZV vasculopathy and giant cell arteritis are strongly associated with productive VZV infection in cerebral and temporal arteries, respectively, we evaluated human aortas for VZV antigen and VZV DNA. Using 3 different anti-VZV antibodies, we identified VZV antigen in 11 of 11 aortas with pathologically verified granulomatous arteritis, in 1 of 1 cases of nongranulomatous arteritis, and in 5 of 18 control aortas (28%) obtained at autopsy. The presence of VZV antigen in granulomatous aortitis was highly significant (P = .0001) as compared to control aortas, in which VZV antigen was never associated with pathology, indicating subclinical reactivation. VZV DNA was found in most aortas containing VZV antigen. The frequent clinical, radiological, and pathological aortic involvement in patients with giant cell arteritis correlates with the significant detection of VZV in granulomatous aortitis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.