Evidence map›Paper›PMID 27036114›Full record

ArticleVirology journal2016

Surveillance for Eurasian-origin and intercontinental reassortant highly pathogenic influenza A viruses in Alaska, spring and summer 2015.

Andrew M Ramey, John M Pearce, Andrew B Reeves, Rebecca L Poulson, Jennifer Dobson, Brian Lefferts, Kyle Spragens, David E Stallknecht

Open access · goldAbstract read
In one paragraph

Article in Virology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Andrew M RameyU.S. Geological Survey, Alaska Science Center, 4210 University Drive, Anchorage, AK, 99508, USA. aramey@usgs.gov.
John M PearceU.S. Geological Survey, Alaska Science Center, 4210 University Drive, Anchorage, AK, 99508, USA.
Andrew B ReevesU.S. Geological Survey, Alaska Science Center, 4210 University Drive, Anchorage, AK, 99508, USA.
Rebecca L PoulsonSoutheastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, 589 D. W. Brooks Drive, University of Georgia, Athens, GA, 30602, USA.
Jennifer DobsonYukon-Kuskokwim Health Corporation, 900 Chief Eddie Hoffman Highway, Bethel, AK, 99559, USA.
Brian LeffertsYukon-Kuskokwim Health Corporation, 900 Chief Eddie Hoffman Highway, Bethel, AK, 99559, USA.
Kyle SpragensU.S. Geological Survey, Western Ecological Research Center, San Francisco Bay Estuary, 505 Azuar Drive, Vallejo, CA, 94592, USA.
David E StallknechtSoutheastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, 589 D. W. Brooks Drive, University of Georgia, Athens, GA, 30602, USA.
United States Geological Survey · USUniversity of Georgia · USYukon Kuskokwim Health Corporation · US

Funding

NIAID NIH HHS HHSN272201400006C
6 · The paper itself

Abstract

backgroundEurasian-origin and intercontinental reassortant highly pathogenic (HP) influenza A viruses (IAVs) were first detected in North America in wild, captive, and domestic birds during November-December 2014. Detections of HP viruses in wild birds in the contiguous United States and southern Canadian provinces continued into winter and spring of 2015 raising concerns that migratory birds could potentially disperse viruses to more northerly breeding areas where they could be maintained to eventually seed future poultry outbreaks.

resultsWe sampled 1,129 wild birds on the Yukon-Kuskokwim Delta, Alaska, one of the largest breeding areas for waterfowl in North America, during spring and summer of 2015 to test for Eurasian lineage and intercontinental reassortant HP H5 IAVs and potential progeny viruses. We did not detect HP IAVs in our sample collection from western Alaska; however, we isolated five low pathogenic (LP) viruses. Four isolates were of the H6N1 (n = 2), H6N2, and H9N2 combined subtypes whereas the fifth isolate was a mixed infection that included H3 and N7 gene segments. Genetic characterization of these five LP IAVs isolated from cackling (Branta hutchinsii; n = 2) and greater white-fronted geese (Anser albifrons; n = 3), revealed three viral gene segments sharing high nucleotide identity with HP H5 viruses recently detected in North America. Additionally, one of the five isolates was comprised of multiple Eurasian lineage gene segments.

conclusionsOur results did not provide direct evidence for circulation of HP IAVs in the Yukon-Kuskokwim Delta region of Alaska during spring and summer of 2015. Prevalence and genetic characteristics of LP IAVs during the sampling period are concordant with previous findings of relatively low viral prevalence in geese during spring, non-detection of IAVs in geese during summer, and evidence for intercontinental exchange of viruses in western Alaska.

Indexed as

GenotypeAlaskaAnimalsBirdsEpidemiological MonitoringInfluenza A virusInfluenza in BirdsMolecular EpidemiologyReassortant VirusesSequence Analysis, DNAAlaskaH5N1H5N2H5N8Highly pathogenicInfluenzaMigratory birdYukon-Kuskokwim Delta

Identifiers

PMID27036114
PMCPMC4815243
OpenAlexW2321495601

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.