Evidence map›Paper›PMID 27036102›Full record

ArticleCritical care (London, England)2016

Development of an algorithm to aid triage decisions for intensive care unit admission: a clinical vignette and retrospective cohort study.

Joao Gabriel Rosa Ramos, Beatriz Perondi, Roger Daglius Dias, Leandro Costa Miranda, Claudio Cohen, Carlos Roberto Ribeiro Carvalho, Irineu Tadeu Velasco, Daniel Neves Forte

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  9. Identifying ICU admission decision patterns in a '20-questions game' approach using network analysis.The Southern African journal of critical care : the official journal of the Critical Care Society · 2021
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  11. Decision-making in the ICU: An analysis of the ICU admission decision-making process using a '20 Questions' approach.The Southern African journal of critical care : the official journal of the Critical Care Society · 2020
    Article
  12. Article
  13. The Critical Care Society of Southern Africa Consensus Statement on ICU Triage and Rationing (ConICTri).The Southern African journal of critical care : the official journal of the Critical Care Society · 2019
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  14. The Critical Care Society of Southern Africa Consensus Guideline on ICU Triage and Rationing (ConICTri).The Southern African journal of critical care : the official journal of the Critical Care Society · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Joao Gabriel Rosa RamosMedical sciences doctoral program, University of Sao Paulo Medical School, Sao Paulo, Brazil. jgrr25@gmail.com.ORCID http://orcid.org/0000-0003-2201-9872
Beatriz PerondiEmergency Department, Hospital das Clinicas, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Roger Daglius DiasEmergency Department, Hospital das Clinicas, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Leandro Costa MirandaIntensive Care Unit, Hospital Nove de Julho, Sao Paulo, Brazil.
Claudio CohenBioethics Committee, Hospital das Clinicas, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Carlos Roberto Ribeiro CarvalhoPulmonary Division, Heart Institute (InCor), Hospital das Clinicas, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Irineu Tadeu VelascoIntensive Care Unit, Emergency Medicine Discipline, Hospital das Clinicas, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Daniel Neves ForteIntensive Care Unit, Emergency Medicine Discipline, Hospital das Clinicas, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversidade de São Paulo · BRUniversidade Nove de Julho · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntensive care unit (ICU) admission triage is performed routinely and is often based solely on clinical judgment, which could mask biases. A computerized algorithm to aid ICU triage decisions was developed to classify patients into the Society of Critical Care Medicine's prioritization system. In this study, we sought to evaluate the reliability and validity of this algorithm.

methodsNine senior physicians evaluated forty clinical vignettes based on real patients. The reference standard was defined as the priorities ascribed by two investigators with full access to patients' records. Agreement of algorithm-based priorities with the reference standard and with intuitive priorities provided by the physicians were evaluated. Correlations between algorithm prioritization and physicians' judgment of the appropriateness of ICU admissions in scarcity and nonscarcity settings were also evaluated. Validity was further assessed by retrospectively applying this algorithm to 603 patients with requests for ICU admission for association with clinical outcomes.

resultsAgreement between algorithm-based priorities and the reference standard was substantial, with a median κ of 0.72 (interquartile range [IQR] 0.52-0.77). Algorithm-based priorities demonstrated higher interrater reliability (overall κ 0.61, 95% confidence interval [CI] 0.57-0.65; median percentage agreement 0.64, IQR 0.59-0.70) than physicians' intuitive prioritization (overall κ 0.51, 95% CI 0.47-0.55; median percentage agreement 0.49, IQR 0.44-0.56) (p = 0.001). Algorithm-based priorities were also associated with physicians' judgment of appropriateness of ICU admission (priorities 1, 2, 3, and 4 vignettes would be admitted to the last ICU bed in 83.7%, 61.2%, 45.2%, and 16.8% of the scenarios, respectively; p < 0.001) and with actual ICU admission, palliative care consultation, and hospital mortality in the retrospective cohort.

conclusionsThis ICU admission triage algorithm demonstrated good reliability and validity. However, more studies are needed to evaluate a difference in benefit of ICU admission justifying the admission of one priority stratum over the others.

Indexed as

AlgorithmsClinical Decision-MakingCohort StudiesCritical CareCritical IllnessFemaleHumansIntensive Care UnitsMalePatient AdmissionRetrospective StudiesSurvival AnalysisTreatment Outcome

Identifiers

PMID27036102
PMCPMC4818478
OpenAlexW2321635016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.