ArticleOncotarget2016
Marital status independently predicts pancreatic cancer survival in patients treated with surgical resection: an analysis of the SEER database.
Article in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Marital status and survival in cancer patients: A systematic review and meta-analysis.Cancer medicine · 2023Pooled it
- Development of a prognostic nomogram for metastatic pancreatic ductal adenocarcinoma integrating marital status.Scientific reports · 2022Trial
- Diabetes mellitus, ABO Blood groups, and biochemical correlates in pancreatic cancer- A retrospective study from Jeddah.Journal of family medicine and primary care · 2026Article
- The Presence or Absence of Household Members Is a Factor That Influences Treatment Decisions in Patients with Pancreatic Cancer.Internal medicine (Tokyo, Japan) · 2025Article
- Marital status as an independent prognostic factor in male breast cancer: a SEER-based cohort study.Breast cancer (Tokyo, Japan) · 2025Article
- Lifestyle Medicine for the Prevention and Treatment of Pancreatitis and Pancreatic Cancer.Diagnostics (Basel, Switzerland) · 2024Review
- Studying the impact of marital status on diagnosis and survival prediction in pancreatic ductal carcinoma using machine learning methods.Scientific reports · 2024Article
- Management of Patients With Pancreatic Cancer Using the "Right Track" Model.The oncologist · 2023Review
- Establishment and validation of systematic prognostic nomograms in patients over 60 years of age with osteosarcoma: A multicenter external verification study.Cancer medicine · 2023Article
- Sex, Gender and Age Differences in Treatment Allocation and Survival of Patients With Metastatic Pancreatic Cancer: A Nationwide Study.Frontiers in oncology · 2022Article
- Clinical Presentation of Hepatocellular Carcinoma in African Americans vs. Caucasians: A Retrospective Analysis.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021Article
- Impact of Socioeconomic Factors on Prognosis and Clinical Management in Patients with Hepatocellular Carcinoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021Article
- Article
- Disparities in the Use of Chemotherapy in Patients with Resected Pancreatic Ductal Adenocarcinoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- Marital Status and Overall Survival in Patients with Resectable Pancreatic Cancer: Results of an Ancillary Analysis of NRG Oncology/RTOG 9704.The oncologist · 2020Article
- Survival outcomes of pancreaticoduodenectomy versus extended pancreaticoduodenectomy procedure for pancreatic head carcinoma: a propensity score matching study.Translational cancer research · 2020Article
- Nomograms predicting long-term survival in patients with invasive intraductal papillary mucinous neoplasms of the pancreas: A population-based study.World journal of gastroenterology · 2020Article
- Prognostic value of COL6A3 in pancreatic adenocarcinoma.Annals of hepato-biliary-pancreatic surgery · 2020Article
- Article
- Marital status is an independent prognostic factor in inflammatory breast cancer patients: an analysis of the surveillance, epidemiology, and end results database.Breast cancer research and treatment · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marital status is an independent prognostic factor for survival in several cancers. To determine if that is also true for pancreatic cancer after surgical treatment, we examined 13,370 cases of pancreatic cancer reported to the Surveillance, Epidemiology, and End Results (SEER) database between 1988 and 2012. We found that patients who were widowed at the time of diagnosis were more likely to be female, a high percentage were elderly, a high ratio were diagnosed in early years, and a high proportion of tumors were located at the head of the pancreas (P < 0.05). Marital status was confirmed to be an independent prognostic factor in both univariate and multivariate analyses (P < 0.05). In those with localized disease, 5-year pancreatic cancer cause-specific survival was 6.5% lower in widowed patients than married ones (38.6% vs. 32.1%), though this difference was not significant in a multivariate analysis (P = 0.084). In those with regional disease or distant metastasis, univariate and multivariate analyses indicated marital status to be an independent prognostic factor (P < 0.05). Thus marital status is an important prognostic factor in pancreatic cancer, and widowed patients are at greater risk of death than others.
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