ArticleProceedings of the National Academy of Sciences of the United States of America2016
Host-parasite oscillation dynamics and evolution in a compartmentalized RNA replication system.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Parasites constrain within-population diversification while accelerating between-population divergence in an RNA replication system.Molecular biology and evolution · 2026Article
- A symbiotic origin of the ribosome?PNAS nexus · 2026Article
- Selective peptide bond formation via side chain reactivity and self-assembly of abiotic phosphates.Nature communications · 2025Article
- RNA World with Inhibitors.Entropy (Basel, Switzerland) · 2024Article
- Protocell Effects on RNA Folding, Function, and Evolution.Accounts of chemical research · 2024Article
- Effect of montmorillonite K10 clay on RNA structure and function.Biophysical journal · 2024Article
- The RNA-DNA world and the emergence of DNA-encoded heritable traits.RNA biology · 2024Article
- Mixed anhydrides at the intersection between peptide and RNA autocatalytic sets: evolution of biological coding.Interface focus · 2023Article
- Periodic temperature changes drive the proliferation of self-replicating RNAs in vesicle populations.Nature communications · 2023Article
- Progresses in Cell-Free In Vitro Evolution.Advances in biochemical engineering/biotechnology · 2023Review
- Plausible pathway for a host-parasite molecular replication network to increase its complexity through Darwinian evolution.PLoS computational biology · 2022Article
- RNA World Modeling: A Comparison of Two Complementary Approaches.Entropy (Basel, Switzerland) · 2022Article
- In vitro characterisation of the MS2 RNA polymerase complex reveals host factors that modulate emesviral replicase activity.Communications biology · 2022Article
- Evolutionary transition from a single RNA replicator to a multiple replicator network.Nature communications · 2022Article
- A scaling law of multilevel evolution: how the balance between within- and among-collective evolution is determined.Genetics · 2022Article
- An Approach to the De Novo Synthesis of Life.Accounts of chemical research · 2022Article
- Vesicle encapsulation stabilizes intermolecular association and structure formation of functional RNA and DNA.Current biology : CB · 2022Article
- How evolution builds up complexity?: In vitro evolution approaches to witness complexification in artificial molecular replication systems.Biophysics and physicobiology · 2022Article
- Sequencing the origins of life.BBA advances · 2022Review
- Chemical Fueling Enables Molecular Complexification of Self-Replicators*.Angewandte Chemie (International ed. in English) · 2021Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
To date, various cellular functions have been reconstituted in vitro such as self-replication systems using DNA, RNA, and proteins. The next important challenges include the reconstitution of the interactive networks of self-replicating species and investigating how such interactions generate complex ecological behaviors observed in nature. Here, we synthesized a simple replication system composed of two self-replicating host and parasitic RNA species. We found that the parasitic RNA eradicates the host RNA under bulk conditions; however, when the system is compartmentalized, a continuous oscillation pattern in the population dynamics of the two RNAs emerges. The oscillation pattern changed as replication proceeded mainly owing to the evolution of the host RNA. These results demonstrate that a cell-like compartment plays an important role in host-parasite ecological dynamics and suggest that the origin of the host-parasite coevolution might date back to the very early stages of the evolution of life.
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