Trial reportJournal of pediatric gastroenterology and nutrition2016
Effect of Psychotherapy on Health Care Utilization in Children With Inflammatory Bowel Disease and Depression.
Trial report in Journal of pediatric gastroenterology and nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Psychological interventions for treatment of inflammatory bowel disease.The Cochrane database of systematic reviews · 2025Pooled it
- Psychological therapies for anxiety and depression in children and adolescents with long-term physical conditions.The Cochrane database of systematic reviews · 2018Pooled it
- Quality of life during usual epilepsy care for anxiety or depression symptoms: Secondary patient-reported outcomes in a randomized trial of remote assessment methods.Epilepsy research · 2024Trial
- Effect of Cognitive Behavioral Therapy on Clinical Disease Course in Adolescents and Young Adults With Inflammatory Bowel Disease and Subclinical Anxiety and/or Depression: Results of a Randomized Trial.Inflammatory bowel diseases · 2019Trial
- Article
- Exploring the management and treatment of IBD from the perspective of psychological comorbidities.Therapeutic advances in gastroenterology · 2024Review
- Symptoms associated with healthcare resource utilization in the setting of inflammatory bowel disease.Scientific reports · 2022Article
- Prevalence and predictors of medication non-adherence in children with inflammatory bowel disease in China: A cross-sectional study.Frontiers in pharmacology · 2022Article
- Promoting psycho-social wellbeing for engaging inflammatory bowel disease patients in their care: an Italian consensus statement.BMC psychology · 2021Article
- The Impact of Psychiatric Comorbidity on Health Care Utilization in Inflammatory Bowel Disease: A Population-based Study.Inflammatory bowel diseases · 2021Article
- Effect of mood and anxiety disorders on health care utilization in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2021Article
- Leveraging Institutional Support to Build an Integrated Multidisciplinary Care Model in Pediatric Inflammatory Bowel Disease.Children (Basel, Switzerland) · 2021Article
- Depression Predicts Prolonged Length of Hospital Stay in Pediatric Inflammatory Bowel Disease.Journal of pediatric gastroenterology and nutrition · 2019Article
- Hospital Readmission of Adolescents and Young Adults With Complex Chronic Disease.JAMA network open · 2019Article
- Effects of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Gut Microbiota in a Rat Model of Depression.Clinical pharmacology and translational medicine · 2019Article
- Ketamine interactions with gut-microbiota in rats: relevance to its antidepressant and anti-inflammatory properties.BMC microbiology · 2018Article
- Phase I of the Detecting and Evaluating Childhood Anxiety and Depression Effectively in Subspecialties (DECADES) Study: Development of an Integrated Mental Health Care Model for Pediatric Gastroenterology.Journal of participatory medicine · 2018Article
- Depression Is Associated With More Aggressive Inflammatory Bowel Disease.The American journal of gastroenterology · 2018Article
- Mind-Body Interventions for Pediatric Inflammatory Bowel Disease.Children (Basel, Switzerland) · 2017Review
- Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
objectivesPediatric patients with inflammatory bowel disease (IBD) are at an increased risk of developing depression compared with community controls. Depression often negatively influences illness behaviors such as resource utilization. We sought to investigate the effects of treating depression on utilization of medical resources in depressed pediatric patients with IBD by comparing rates of health care utilization 1 year before and after psychotherapy.
methodTwo hundred seventeen subjects ages 9 to 17 years with IBD and depression received 3 months of psychotherapy for depression as part of a multicenter randomized controlled trial. Of these 217 subjects, 70 had utilization data available 1 year prior and 1 year after receiving 3 months of psychotherapy. Primary outcomes included frequency of hospitalizations, inpatient hospital days, outpatient gastrointestinal visits, and number of emergency room visits, radiological examinations, and endoscopies. Within subject analyses were completed comparing health care utilization 12 months before psychotherapy compared with the 12 months after the conclusion of psychotherapy.
resultsFifty-one and 19 patients had CD and UC, respectively. A total of 55.7% of patients had major depression and 44.3% had minor depression. Overall, all study measures of health care utilization were significantly reduced after psychotherapy (P < 0.01)-including gastrointestinal-related (mean values) hospitalization frequency, inpatient days, outpatient visit, emergency room visits, radiological examinations, and endoscopies.
conclusionsPsychotherapy for comorbid depression in pediatric patients with IBD is associated with decreased GI-related health care utilization. The present study highlights the importance of screening for depression in a pediatric population with IBD, and that psychotherapy may be a reasonable adjunctive treatment for pediatric patients with IBD and comorbid depression.
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