ArticleCritical care medicine2016
Low Tidal Volume Ventilation Use in Acute Respiratory Distress Syndrome.
Article in Critical care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
70 citing papers in PubMed.
- Nudging implementation of low tidal volume ventilation: a stepped wedge, cluster randomized trial.Implementation science : IS · 2026Trial
- Delivery of Lung-protective Ventilation for Acute Respiratory Distress Syndrome: A Hybrid Implementation-Effectiveness Trial.Annals of the American Thoracic Society · 2023Trial
- ICU Implementation Determinants and Delivery of Lung Protective Ventilation: A Multihospital Survey and Cohort Study.CHEST critical care · 2026Article
- Review
- Multimodal Deep Learning for ARDS Detection.medRxiv : the preprint server for health sciences · 2025Article
- Open-source computational pipeline flags instances of acute respiratory distress syndrome in mechanically ventilated adult patients.Nature communications · 2025Article
- Impact of a Competency-based Mechanical Ventilation Course Using Virtual Simulation.ATS scholar · 2025Article
- Development and External Validation of a Detection Model to Retrospectively Identify Patients With Acute Respiratory Distress Syndrome.Critical care medicine · 2025Article
- Article
- Computationally-directed mechanical ventilation in a porcine model of ARDS.Frontiers in physiology · 2025Article
- The implementation gap in critical care: From nutrition to ventilation.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025Article
- A dynamic customized electronic health record rule based clinical decision support tool for standardized adult intensive care metrics.JAMIA open · 2024Article
- Design and Implementation of an Intensive Care Unit Command Center for Medical Data Fusion.Sensors (Basel, Switzerland) · 2024Article
- Eye on the Prize: Patient Outcomes Research in Medical Education.ATS scholar · 2024Article
- Long short-term memory model identifies ARDS and in-hospital mortality in both non-COVID-19 and COVID-19 cohort.BMJ health & care informatics · 2023Article
- Validation of a tool for estimating clinician recognition of ARDS using data from the international LUNG SAFE study.PLOS digital health · 2023Article
- A Pilot Standardized Simulation-Based Mechanical Ventilation Curriculum Targeting Pulmonary and Critical Care Medicine and Critical Care Medicine Fellows.Avicenna journal of medicine · 2023Article
- Applying Intersectionality to Better Characterize Healthcare Disparities for Critically Ill Adults.American journal of respiratory and critical care medicine · 2023Article
- Disparities Exist in the Application of Low Tidal-volume Ventilation in the Emergency Department.The western journal of emergency medicine · 2023Observational
- Driving Pressure, Elastance, and Outcomes in a Real-World Setting: A Bi-Center Analysis of Electronic Health Record Data.Critical care explorations · 2023Article
10 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
Funding
Abstract
objectiveLow tidal volume ventilation lowers mortality in the acute respiratory distress syndrome. Previous studies reported poor low tidal volume ventilation implementation. We sought to determine the rate, quality, and predictors of low tidal volume ventilation use.
designRetrospective cross-sectional study.
settingOne academic and three community hospitals in the Chicago region. PATIENTS: A total of 362 adults meeting the Berlin Definition of acute respiratory distress syndrome consecutively admitted between June and December 2013. MEASUREMENTS AND MAIN
resultsSeventy patients (19.3%) were treated with low tidal volume ventilation (tidal volume < 6.5 mL/kg predicted body weight) at some time during mechanical ventilation. In total, 22.2% of patients requiring an FIO2 greater than 40% and 37.3% of patients with FIO2 greater than 40% and plateau pressure greater than 30 cm H2O received low tidal volume ventilation. The entire cohort received low tidal volume ventilation 11.4% of the time patients had acute respiratory distress syndrome. Among patients who received low tidal volume ventilation, the mean (SD) percentage of acute respiratory distress syndrome time it was used was 59.1% (38.2%), and 34% waited more than 72 hours prior to low tidal volume ventilation initiation. Women were less likely to receive low tidal volume ventilation, whereas sepsis and FIO2 greater than 40% were associated with increased odds of low tidal volume ventilation use. Four attending physicians (6.2%) initiated low tidal volume ventilation within 1 day of acute respiratory distress syndrome onset for greater than or equal to 50% of their patients, whereas 34 physicians (52.3%) never initiated low tidal volume ventilation within 1 day of acute respiratory distress syndrome onset. In total, 54.4% of patients received a tidal volume less than 8 mL/kg predicted body weight, and the mean tidal volume during the first 72 hours after acute respiratory distress syndrome onset was never less than 8 mL/kg predicted body weight.
conclusionsMore than 12 years after publication of the landmark low tidal volume ventilation study, use remains poor. Interventions that improve adoption of low tidal volume ventilation are needed.
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