Evidence map›Paper›PMID 27035119›Full record

ArticleScientific reports2016

Evaluation of genetic diversity among strains of the human gut commensal Bifidobacterium adolescentis.

Sabrina Duranti, Christian Milani, Gabriele Andrea Lugli, Leonardo Mancabelli, Francesca Turroni, Chiara Ferrario, Marta Mangifesta, Alice Viappiani, Borja Sánchez, Abelardo Margolles and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 118 citations in OpenAlex.

  1. Trial
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  4. Review
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  6. Article
  7. Article
  8. Article
  9. Article
  10. Gene-trait matching amongFrontiers in microbiology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Ecology- and genome-based identification of theApplied and environmental microbiology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Sabrina DurantiLaboratory of Probiogenomics, Department of Life Sciences, University of Parma, Italy.
Christian MilaniLaboratory of Probiogenomics, Department of Life Sciences, University of Parma, Italy.
Gabriele Andrea LugliLaboratory of Probiogenomics, Department of Life Sciences, University of Parma, Italy.
Leonardo MancabelliLaboratory of Probiogenomics, Department of Life Sciences, University of Parma, Italy.
Francesca TurroniLaboratory of Probiogenomics, Department of Life Sciences, University of Parma, Italy.
Chiara FerrarioLaboratory of Probiogenomics, Department of Life Sciences, University of Parma, Italy.
Marta MangifestaGenProbio srl, Parma, Italy.
Alice ViappianiGenProbio srl, Parma, Italy.
Borja SánchezDepartamento de Microbiologia y Bioquimica de Productos Lacteos, IPLA - CSIC, Villaviciosa, Asturias, Spain.
Abelardo MargollesDepartamento de Microbiologia y Bioquimica de Productos Lacteos, IPLA - CSIC, Villaviciosa, Asturias, Spain.
Douwe van SinderenAPC Microbiome Institute and School of Microbiology, National University of Ireland, Cork, Ireland.
Marco VenturaLaboratory of Probiogenomics, Department of Life Sciences, University of Parma, Italy.
University of Parma · ITInstituto de Productos Lácteos de Asturias · ESAPC Microbiome Institute · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bifidobacteria are members of the human gut microbiota, being numerically dominant in the colon of infants, while also being prevalent in the large intestine of adults. In this study, we determined and analyzed the pan-genome of Bifidobacterium adolescentis, which is one of many bacteria found in the human adult gut microbiota. In silico analysis of the genome sequences of eighteen B. adolescentis strains isolated from various environments, such as human milk, human feces and bovine rumen, revealed a high level of genetic variability, resulting in an open pan-genome. Compared to other bifidobacterial taxa such as Bifidobacterium bifidum and Bifidobacterium breve, the more extensive B. adolescentis pan-genome supports the hypothesis that the genetic arsenal of this taxon expanded so as to become more adaptable to the variable and changing ecological niche of the gut. These increased genetic capabilities are particularly evident for genes required for dietary glycan-breakdown.

Indexed as

Gastrointestinal MicrobiomeGenetic VariationAnimalsBifidobacterium adolescentisCarbohydratesCattleDietDNA, BacterialFecesGenome, BacterialGenomicsHumansIntestinesMilkOpen Reading FramesPolysaccharidesCarbohydratesDNA, BacterialPolysaccharides

Identifiers

PMID27035119
PMCPMC4817515
OpenAlexW2314088936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.