Evidence map›Paper›PMID 27034820›Full record

ArticleJournal of gastrointestinal oncology2016

A case of peripheral T-cell lymphoma, not otherwise specified in a HCV and HTLV-II-positive patient, diagnosed by abdominal fluid cytology.

Maryam Dadfarnia Ameri, Trisha M Parekh, You-Wen Qian, M Tarek Elghetany, Vicki Schnadig, Ranjina Nawgiri

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of gastrointestinal oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Maryam Dadfarnia Ameri1 Department of Pathology, City of Hope National Medical Center, Duarte, USA ; 2 Department of Internal medicine, 3 Department of Pathology, University of Texas Medical Branch, Galveston, USA ; 4 Department of Pathology & Immunology, Baylor College of Medicine, Houston, USA.
Trisha M Parekh1 Department of Pathology, City of Hope National Medical Center, Duarte, USA ; 2 Department of Internal medicine, 3 Department of Pathology, University of Texas Medical Branch, Galveston, USA ; 4 Department of Pathology & Immunology, Baylor College of Medicine, Houston, USA.
You-Wen Qian1 Department of Pathology, City of Hope National Medical Center, Duarte, USA ; 2 Department of Internal medicine, 3 Department of Pathology, University of Texas Medical Branch, Galveston, USA ; 4 Department of Pathology & Immunology, Baylor College of Medicine, Houston, USA.
M Tarek Elghetany1 Department of Pathology, City of Hope National Medical Center, Duarte, USA ; 2 Department of Internal medicine, 3 Department of Pathology, University of Texas Medical Branch, Galveston, USA ; 4 Department of Pathology & Immunology, Baylor College of Medicine, Houston, USA.
Vicki Schnadig1 Department of Pathology, City of Hope National Medical Center, Duarte, USA ; 2 Department of Internal medicine, 3 Department of Pathology, University of Texas Medical Branch, Galveston, USA ; 4 Department of Pathology & Immunology, Baylor College of Medicine, Houston, USA.
Ranjina Nawgiri1 Department of Pathology, City of Hope National Medical Center, Duarte, USA ; 2 Department of Internal medicine, 3 Department of Pathology, University of Texas Medical Branch, Galveston, USA ; 4 Department of Pathology & Immunology, Baylor College of Medicine, Houston, USA.
The University of Texas Medical Branch at Galveston · USBaylor College of Medicine · USCity Of Hope National Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) is a rare neoplasm that typically presents as generalized lymphadenopathy. PTCL, NOS presenting as malignant ascites is rare.

methodsA 61-year-old African-American man with past medical history of HCV, cryoglobulinemia, and cryptococcal pneumonia was admitted for dyspnea on exertion over a period of 1 month and new onset of abdominal distension.

resultsAscites, splenomegaly, hepatomegaly and extensive lymphadenopathy were found by imaging. Paracentesis obtained 1.3 liter of abdominal fluid, the cytologic evaluation showed a monomorphic population of intermediate-sized lymphoid cells with irregular to convoluted nuclear contours. Fluid sent for flow cytometry showed an abnormal T-lymphocyte population expressing CD4, weak surface CD3 and absence of CD7. PCR studies of ascitic fluid detected a clonal T-lymphocyte population with T-cell receptor gamma gene rearrangement. Serologic testing for human T lymphotropic virus (HTLV) was positive for HTLV-II. Subsequent bone marrow biopsy revealed lymphomatous involvement. CD30 and ALK-1 immunostaining were negative. This case was classified as PTCL, NOS.

conclusionsPTCL, NOS can have unusual clinical presentation such as ascites and pleural effusion, and may also occur as a complication of immunodeficiency state. Further studies are needed to determine if HCV or HTLV-II viral infection is associated with PTCL.

Indexed as

asciteshuman T lymphotropic virus II (HTLV-II)Peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS)

Identifiers

PMID27034820
PMCPMC4783614
OpenAlexW2175535659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.