ArticleJournal of gastrointestinal oncology2016
Gastrointestinal stromal tumor with an unusual presentation as an enlarged prostate gland: a case report and review of the literature.
Article in Journal of gastrointestinal oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Patient-derived xenograft models of gastrointestinal stromal tumors provide a ready-to-use platform for translational research.Disease models & mechanisms · 2025Article
- Primary extragastrointestinal stromal tumor of the prostate: review of the literature and case report.Annals of medicine and surgery (2012) · 2023Article
- Primary extragastrointestinal stromal tumors of the prostate: A case report and literature review.Frontiers in oncology · 2022Article
- Current knowledge of primary prostatic extra-gastrointestinal stromal tumor: a case report and review of the literature.The Journal of international medical research · 2021Review
- Review
- Primary Prostatic Extra-Gastrointestinal Stromal Tumor Treated with Imatinib Mesylate as Neoadjuvant and Adjuvant Therapy: A Case Report and Literature Review.OncoTargets and therapy · 2019Article
- Extragastrointestinal stromal tumor of the abdominal subcutaneous tissue: Report of a very rare case at an unusual site.The Journal of international medical research · 2017Article
- Diagnosis and treatment of gastrointestinal stromal tumor extending to prostate: A case report and literature review.Medicine · 2016Article
- Rectal gastrointestinal stromal tumor with metastasis to the penis: Case report and review of literature.International journal of surgery case reports · 2016Article
- Successful Perioperative and Surgical Treatment of a Rare Case of Extra-Gastrointestinal Stromal Tumor Arising in the Prostate Gland.Case reports in oncologyArticle
- Gastrointestinal stromal tumor presenting with lower urinary tract symptoms - A series of five cases with unusual clinical presentation.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case of a 78-year-old male who presented with urinary retention, constipation and an enlarged prostate gland. A transurethral resection of the prostate (TURP) was performed. Pathologic examination revealed a hypercellular-spindled neoplasm with frequent mitoses, nuclear pleomorphism, and multifocal geographic tumoral necrosis. A pathologic diagnosis of gastrointestinal stromal tumor (GIST) was made based on morphologic and immunohistochemical findings, and was later reinforced by molecular study results. This lesion was initially thought to represent a primary prostatic GIST. To the best of our knowledge, there have been only five cases of primary prostatic GISTs. Subsequent imaging studies revealed the mass to be contiguous with the anterior rectal wall, suggesting the possibility of a rectal primary with extension to the prostate gland. The patient was treated with imatinib mesylate, and after twelve months of follow up failed to demonstrate any evidence of progression or metastatic disease. GIST should be considered in cases of prostatic tumors with a spindled or epithelioid morphology, and immunohistochemistry and possible molecular studies are recommended to aid in diagnosis and guide treatment decisions.
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