Evidence map›Paper›PMID 27034810›Full record

ReviewJournal of gastrointestinal oncology2016

Diagnosis and differential diagnosis of hepatic graft versus host disease (GVHD).

Karen E Matsukuma, Dongguang Wei, Kai Sun, Rajendra Ramsamooj, Mingyi Chen

Abstract readReview
In one paragraph

Review in Journal of gastrointestinal oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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  11. Acquired ductopenia: an insight into imaging findings.Abdominal radiology (New York) · 2025
    Review
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  19. Immune Checkpoint Inhibitor-Induced Hepatic Injury: A Clinicopathologic Review.Journal of clinical and translational pathology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karen E Matsukuma1 Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA 95817, USA ; 2 Department of Hematology, Zhengzhou University People's Hospital, Zhengzhou 450000, China.
Dongguang Wei1 Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA 95817, USA ; 2 Department of Hematology, Zhengzhou University People's Hospital, Zhengzhou 450000, China.
Kai Sun1 Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA 95817, USA ; 2 Department of Hematology, Zhengzhou University People's Hospital, Zhengzhou 450000, China.
Rajendra Ramsamooj1 Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA 95817, USA ; 2 Department of Hematology, Zhengzhou University People's Hospital, Zhengzhou 450000, China.
Mingyi Chen1 Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA 95817, USA ; 2 Department of Hematology, Zhengzhou University People's Hospital, Zhengzhou 450000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graft versus host disease (GVHD) is a common complication following allogeneic hematopoietic cell transplantation (HCT) that typically manifests as injury to the skin, gastrointestinal mucosa, and liver. In some cases, hepatic GVHD may be histologically indistinguishable from other disorders such as infection and drug-induced liver injury (DILI). Additionally, clinical signs and symptoms are frequently confounded by the superimposed effects of pretransplant chemoradiotherapy, immunotherapy (IT) (targeted to the underlying malignancy), GVHD prophylaxis, and infection. Thus, careful attention to and correlation with clinical findings, laboratory values, and histologic features is essential for diagnosis. This review, aimed at the practicing pathologist, will discuss current clinical and histologic criteria for GVHD, the approach to diagnosis of hepatic GVHD, and features helpful for distinguishing it from other entities in the differential diagnosis.

Indexed as

drug-induced liver injury (DILI)graft versus host disease (GVHD)Hematopoietic cell transplantation (HCT)hepatic lymphomaimmunotherapy (IT)post-transplant lymphoproliferative disorder (PTLD)veno-occlusive hepatic disease

Identifiers

PMID27034810
PMCPMC4783620

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.