ArticleTherapeutic advances in drug safety2016
Drug-induced falls in older persons: is there a role for therapeutic drug monitoring?
Article in Therapeutic advances in drug safety, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Cost-utility of medication withdrawal in older fallers: results from the improving medication prescribing to reduce risk of FALLs (IMPROveFALL) trial.BMC geriatrics · 2016Trial
- Candidate genetic variants and antidepressant-related fall risk in middle-aged and older adults.PloS one · 2022Article
- Fall and risk factors for veterans and non-veterans inpatients over the age of 65 years: 14 years of long-term data analysis.BMJ open · 2019Article
- The effect of pregabalin treatment on balance and gait in patients with chronic low back pain: a retrospective observational study.Journal of drug assessment · 2019Article
- Factors associated with falls in older adults with cancer: a validated model from the Cancer and Aging Research Group.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFalls are the leading cause of injuries among older persons. Because of ageing societies worldwide, falls are expected to become a prominent public health problem. The usage of several types of drugs has been associated with an increased fall and fracture risk. In order to reduce future falls, preventative measures are needed. Therapeutic drug monitoring may help to identify persons who are at risk for falls due to drug use. The aim was to demonstrate how drugs can contribute to falls and the role of therapeutic drug monitoring.
methodsWe present a descriptive case series of four patients.
resultsAll patients were referred to the geriatric outpatient clinic of a university medical center. The presented cases contained different underlying mechanisms contributing to an increased fall risk in older adults, including renal failure, genetic variation, overdose and ageing. CONCLUSION/DISCUSSION: Older adults are more prone to the side effects of drug use, including falls. Therapeutic drug monitoring may be useful to identify the patients who have an increased drug-related fall risk and to prevent future falls by individualizing the drug regime.
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