Evidence map›Paper›PMID 27034741›Full record

ReviewOxidative medicine and cellular longevity2016

Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds.

Sandeep Kumar Singh, Saurabh Srivastav, Amarish Kumar Yadav, Saripella Srikrishna, George Perry

Abstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Article
  2. Alzheimer's disease: unraveling role of xanthone derivatives and nanocarriers.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  3. Article
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  5. Review
  6. Review
  7. Discovery of a Novel spACS medicinal chemistry letters · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Rejuvenating aged microglia by p16Molecular neurodegeneration · 2024
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandeep Kumar SinghDepartment of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, India.
Saurabh SrivastavDepartment of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, India.
Amarish Kumar YadavDepartment of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, India.
Saripella SrikrishnaDepartment of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, India.
George PerryDepartment of Biology, The University of Texas at San Antonio, San Antonio, TX 78249, USA.

Funding

RCMI Center for Interdiscplinary Health Research CIHRG12MD007591 · NIMHD · UNIVERSITY OF TEXAS SAN ANTONIO · PI PERRY, GEORGE · 2012 to 2016
$10.4M
NIMHD NIH HHS G12 MD007591NIMHD NIH HHS G12MD007591
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a complex age-related neurodegenerative disease. In this review, we carefully detail amyloid-β metabolism and its role in AD. We also consider the various genetic animal models used to evaluate therapeutics. Finally, we consider the role of synthetic and plant-based compounds in therapeutics.

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsDisease Models, AnimalDrug Evaluation, PreclinicalHumansPhytotherapyAmyloid beta-Peptides

Identifiers

PMID27034741
PMCPMC4807045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.