ArticlePharmacognosy research
Standardization of Unani Antidiabetic Tablet - Qurse Tabasheer.
Article in Pharmacognosy research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 29 citations in OpenAlex.
- Nutrients and phytochemicals characterisations, acute and sub-acute oral toxicity studies of BobyGuard C, a polyherbal nutraceutical with anti-breast cancer properties.Frontiers in toxicology · 2025Article
- Common Ayurvedic, Chinese traditional and Unani antidiabetic formulations- a review.Frontiers in pharmacology · 2022Review
- Development of Validated High-performance Thin-layer Chromatography Method for Simultaneous Determination of Quercetin and Kaempferol inPharmacognosy researchArticle
- Pharmaceutico-analytical Study ofJournal of pharmacy & bioallied sciencesArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuality control of Unani polyherbal formulations is the need of the day for better acceptance of Unani medicine. Qurse Tabasheer (QT) is a Unani polyherbal formulation containing six ingredients, Tabasheer (Siliceous concretions) (Bambosa arundinaceae Retz.), Gule Surkh (Rosa damascena Mill. flower), Gulnar (Punica granatum Linn. flower), Tukhme kahu (Lactuca sativa Linn. seed), Tukhme khurfa (Portulaca oleraceae Linn. seed), and Gile Armani (bole) widely used in treatment of diabetes. The present study was taken up to scientifically evaluate the various physicochemical parameters to standardize the formulation.
objectiveTo evaluate various physicochemical parameters including ash values, moisture content, extractive values, thin layer chromatography (TLC) and high-performance TLC (HPTLC), friability, disintegration, uniformity, and weight variation for standardization of QT. MATERIALS AND
methodsIngredients were identified by the experts. The method mentioned in national formulary of Unani Medicine with modification was followed for preparation of the tablets. Physicochemical standards were established for ideal batch of tablets on the basis of set parameters regarding friability, hardness, and disintegration. Various parameters such as organoleptic characters, extractive values for the extract and HPTLC fingerprinting postcompression were carried out for evaluation of QT.
resultsParameters for loss of weight on drying, pH, ash values, extractive values documented. Qualitative chemical tests indicated the presence of alkaloid, glycoside, tannins, and steroids. TLC and HPTLC fingerprinting studies showing the presence of major peaks were documented. Friability, hardness, and disintegration time of ideal batch was 0.09 ± 0.0057, 4.03 ± 0.087, and 25.57 ± 0.4860 min, respectively, and it was found to be within the set limit. Weight variation was <5%. Total fungal and bacterial counts were found to be within the limit.
conclusionStandards were established for poly herbal formulation QT, which may be used as reference for preparation and standardization of QT. SUMMARY: In this work Standardization of anti-diabetic tablet Qurse Tabasheer with diverse ingredients including herbal and mineral origin drugs has been attempted with identification of its ingredients, formulation, physicochemical evaluation and HPTLC finger printing, which may help in preparing consistent and better efficacious formulations. Abbreviations Used: QT: Qurse Tabasheer TLC: thin layer chromatography HPTLC: high-performance thin layer chromatography WHO: World health organization FRLHT: Foundation for Revitalization of Local Health Traditions Fe2O3: Iron oxide Sio2: Silica CaCo3: Calcium carbonate, Tio2: Titanium Oxide NIUM: National Institute of Unani Medicine #: Mesh size LOD: Loss of weight on drying USP: United state Pharmacopeia UV: Ultra Violet λ: Lambda θ: theta CFU: Colony-forming unit.
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