ArticleEye (London, England)2016
Prevalence of reticular pseudodrusen in newly presenting adult onset foveomacular vitelliform dystrophy.
Article in Eye (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Non neovascular Age - related macular degeneration - Review on clinical and imaging advances.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
- Adult-onset foveomacular vitelliform dystrophy: epidemiology, pathophysiology, imaging, and prognosis.Frontiers in ophthalmology · 2023Review
- Retinal Metabolic Profile on IMPG2 Deficiency Mice with Subretinal Lesions.Advances in experimental medicine and biology · 2023Article
- Reticular Pseudodrusen in Late-Onset Retinal Degeneration.Ophthalmology. Retina · 2021Article
- LXA4 protects against blue-light induced retinal degeneration in human A2E-laden RPE cells and Balb-c mice.Annals of translational medicine · 2021Article
- Haller's vessels patterns in non-neovascular age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Natural course of adult-onset vitelliform lesions in eyes with and without comorbid subretinal drusenoid deposits.International ophthalmology · 2020Article
- Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Spotlight on reticular pseudodrusen.Clinical ophthalmology (Auckland, N.Z.) · 2017Review
- Subretinal drusenoid deposits: An update.Taiwan journal of ophthalmologyReview
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PurposeTo report the association and prevalence of reticular pseudodrusen (RPD) in eyes with newly presenting adult onset foveomacular vitelliform dystrophy (AFVD). To compare the strength of association with other pathologies resulting from dysfunction of the choroid-Bruch's membrane-retinal pigment epithelium (RPE) complex, including eyes with geographic atrophy (GA) and angioid streaks.MethodsRetrospective single-centre review of all consecutive newly presenting AFVD. Multimodal imaging with spectral domain optical coherence tomography, fundus photographs, red-free/blue light images, and fundus fluorescein angiograms were graded for the presence of RPD. For comparison, all consecutive newly presenting cases of GA and eyes with angioid streaks were studied.ResultsFifteen (15) patients were identified with AFVD (mean age of 77.3 years; 73.3% female). Mean age of patients with AFVD and RPD was 80.5 years (SD 3.7), whereas that of patients with AFVD without RPD was 75.1 years (SD 7.0). This age difference did not reach statistical significance, P=0.1. Six (40%) had identifiable RPD; being a bilateral finding in 100% of patients. No males with AFVD and RPD were identified. A total of 92 eyes presented with GA. Twenty-three (23) of these (25.0%) had RPD. Twelve (12) patients presented with identifiable angioid streaks, with 4 (36.4%) having RPD.ConclusionRPD are a frequent finding in eyes with newly presenting AFVD; not being restricted to AMD, but a finding common among diseases where pathophysiological mechanisms involve damage to Bruch's membrane and the RPE, whether genetic or degenerative. Our study supports the concept that they occur with high but variable frequencies in eyes with various pathologies.
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