ArticleScientific reports2016
Characteristics and Surgical Outcomes for Primary Malignant Melanoma of the Esophagus.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Weekday of Surgery Affects Postoperative Complications and Long-Term Survival of Chinese Gastric Cancer Patients after Curative Gastrectomy.BioMed research international · 2017Trial
- The first case of primary malignant melanoma of the esophagus to achieve pathologic complete response after preoperative ipilimumab + nivolumab followed by resection.Clinical journal of gastroenterology · 2025Article
- Incidence and survival of patients with primary gastrointestinal melanoma: a population-based study.International journal of colorectal disease · 2023Article
- Primary malignant melanoma of the esophagus combined with squamous cell carcinoma: A case report.World journal of gastrointestinal surgery · 2023Article
- Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy.Journal for immunotherapy of cancer · 2023Article
- Clinicopathological characterization of ten patients with primary malignant melanoma of the esophagus and literature review.World journal of gastrointestinal oncology · 2022Article
- The Thousand Faces of Malignant Melanoma: A Systematic Review of the Primary Malignant Melanoma of the Esophagus.Cancers · 2022Review
- Clinicopathological Features, Staging Classification, and Clinical Outcomes of Esophageal Melanoma: Evaluation of a Pooled Case Series.Frontiers in oncology · 2022Article
- Primary Malignant Melanoma of the Esophagus Presenting as Chronic Cough.ACG case reports journal · 2021Article
- Primary malignant melanoma of the gastroesophageal junction: A rare and unusual disease.Medical journal, Armed Forces India · 2021Article
- Uncommon Subtypes of Malignant Melanomas: A Review Based on Clinical and Molecular Perspectives.Cancers · 2020Review
- Article
- Primary malignant melanoma of the esophagus with multiple lymph node metastases: A case report and literature review.Medicine · 2020Review
- Case Report: Primary melanoma of the gastroesophageal junction.F1000Research · 2020Article
- Endoscopic submucosal dissection of esophageal metastatic melanoma.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2019Article
- Clinicopathological characteristics and survival of primary malignant melanoma of the esophagus.Oncology letters · 2019Article
- Primary malignant melanoma of esophagus: clinicopathologic characterization of 20 cases including molecular genetic profiling of 15 tumors.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2019Article
- Primary malignant melanoma of the esophagus: A retrospective analysis of clinical features, management, and survival of 76 patients.Thoracic cancer · 2019Article
- Malignant melanoma of the esophagus complicated with poorly differentiated mucinous adenocarcinoma of the stomach: A case report.Medicine · 2019Article
- Primary amelanotic malignant melanoma of the esophagus: a case report.Surgical case reports · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary malignant melanoma of the esophagus (PMME) is an extremely rare disease with poor prognosis. We summarized and analyzed the characteristics of 17 PMME patients (with average age of 57.5 ± 10.3 years) who had received surgical resection in our center. The majority (13/17, 76.5%) of the patients were male. The percentage of patients with smoking and alcohol consumption was 41.2% and 23.5%, respectively. The preoperative diagnosis rate was 35.3%. Lymph node metastasis mainly involved the mid-lower mediastinal and upper abdominal area. Primary tumors that invaded beyond the submucosa layer (T2-T4) had much higher tendency of lymph node metastasis than those restricted to the submucosa layer (T1) (6/8, 75.0% vs. 3/9, 33.3%, p = 0.086). The 1-year and 5-year survival rate of the patients was 51% and 10%, respectively, with median survival time being 18.1 months. Survival analysis showed that TNM stage was a predictor for PMME prognosis (median survival time of 47.3 months vs. 8.0 months for stage I/II vs. stage III, respectively, p = 0.018), and multivariable Cox regression analysis revealed the independence of its prognostic value [HR (95% CI): 5.678 (1.125-28.658), p = 0.035].
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