Evidence map›Paper›PMID 27033360›Full record

ReviewNeuromolecular medicine2016

Neuro-protective Mechanisms of Lycium barbarum.

Xiwen Xing, Fenyong Liu, Jia Xiao, Kwok Fai So

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuromolecular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
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  8. Evaluation of the Anti-Alzheimer Activity ofCurrent issues in molecular biology · 2025
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  10. Current pharmaceutical design · 2024
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  14. History and main research of psychoneuroimmunology in China.Brain, behavior, & immunity - health · 2022
    Article
  15. Article
  16. Review
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  18. Review
  19. Review
  20. Neural regeneration research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiwen XingDepartment of Biotechnology, Jinan University, No. 601 Huangpu Avenue West, Guangzhou, 510632, China.
Fenyong LiuDepartment of Biotechnology, Jinan University, No. 601 Huangpu Avenue West, Guangzhou, 510632, China.
Jia XiaoDepartment of Immunobiology, Institute of Tissue Transplantation and Immunology, Jinan University, No. 601 Huangpu Avenue West, Guangzhou, 510632, China. tjxiao@jnu.edu.cn.
Kwok Fai SoGMH Institute of CNS Regeneration, Guangdong Medical Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, 510632, China. hrmaskf@hku.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuronal diseases, including retinal disorders, stroke, Alzheimer's disease, Parkinson's disease and spinal cord injury, affect a large number of people worldwide and cause heavy social and economic burdens. Although many efforts have been made by scientists and clinicians to develop novel drug and healthcare strategies, few of them received satisfactory outcomes to date. Lycium barbarum is a traditional homology of medicine and food in Chinese medicine, with the capability to nourish the eyes, liver and kidneys. Recent studies have also explored its powerful neuro-protective effects on a number of neuronal diseases. In the current review, we collected key recent findings regarding the neuro-protective effects and mechanisms of L. barbarum derivatives, primarily its polysaccharide (LBP) , in some common diseases of the nervous system. A comprehensive comparison with currently available drugs has also been discussed. In general, LBP is a promising neuronal protector with potent ameliorative effects on key pathological events, such as oxidative stress, inflammation, apoptosis and cell death with minimal side effects.

Indexed as

ApoptosisCell DeathHumansInflammationLyciumNeuronsNeuroprotective AgentsOxidative StressPolysaccharidesNeuroprotective AgentsPolysaccharidesLBPLycium barbarumMechanismsNeuro-protective

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.