ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2016
Maternal exercise during pregnancy promotes physical activity in adult offspring.
Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Regular parental pre-mating exercise reduces offspring white adiposity and is associated with hypothalamic neurodevelopmental changes during lactation.Molecular metabolism · 2026Article
- Adherence to dietary and physical activity guidelines and influencing factors among pregnant women: a cross-sectional study in China.Frontiers in nutrition · 2026Article
- Liver as a metabolic sensor in gestational diabetes: Implications for offspring's liver and diabetes risk.World journal of hepatology · 2025Review
- Grandfathers-to-Grandsons Transgenerational Transmission of Exercise Positive Effects on Cognitive Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Offspring sex modifies the association between early-pregnancy adiposity and 2-year-old physical activity-The Glowing Study.International journal of obesity (2005) · 2024Article
- Obesogens: a unifying theory for the global rise in obesity.International journal of obesity (2005) · 2024Review
- Selectively breeding for high voluntary physical activity in female mice does not bestow inherent characteristics that resemble eccentric remodeling of the heart, but the mini-muscle phenotype does.Sports medicine and health science · 2023Article
- Epigenetic modifications and fetal programming: Molecular mechanisms to control hypertension inheritance.Biochemical pharmacology · 2023Review
- Maternal high-intensity interval training as a suitable approach for offspring's heart protection in rat: evidence from oxidative stress and mitochondrial genes.Frontiers in physiology · 2023Article
- Beneficial Effects of Maternal Physical Activity during Pregnancy on Fetal, Newborn, and Child Health: Guidelines for Interventions during the Perinatal Period from the French National College of Midwives.Journal of midwifery & women's health · 2022Article
- DNA Methylation Analysis of Imprinted Genes in the Cortex and Hippocampus of Cross-Fostered Mice Selectively Bred for Increased Voluntary Wheel-Running.Behavior genetics · 2022Article
- Gestational Exercise Increases Male Offspring's Maximal Workload Capacity Early in Life.International journal of molecular sciences · 2022Article
- Animal models of gestational diabetes: characteristics and consequences to the brain and behavior of the offspring.Metabolic brain disease · 2021Review
- Exercise during pregnancy mitigates the adverse effects of maternal obesity on adult male offspring vascular function and alters one-carbon metabolism.Physiological reports · 2020Article
- Effects of maternal and paternal exercise on offspring metabolism.Nature metabolism · 2020Review
- Maternal Programming of Social Dominance via Milk Cytokines.iScience · 2020Article
- Influence of the maternal high-intensity-interval-training on the cardiac Sirt6 and lipid profile of the adult male offspring in rats.PloS one · 2020Article
- Children's Sleep May Depend on Maternal Sleep Duration During Pregnancy: A Retrospective Study.Nature and science of sleep · 2020Article
- DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice.Nature communications · 2019Article
- Risk of hypertension following perinatal adversity: IUGR and prematurity.The Journal of endocrinology · 2019Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Previous rodent studies have shown that maternal voluntary exercise during pregnancy leads to metabolic changes in adult offspring. We set out to test whether maternal voluntary exercise during pregnancy also induces persistent changes in voluntary physical activity in the offspring. Adult C57BL/6J female mice were randomly assigned to be caged with an unlocked (U) or locked (L) running wheel before and during pregnancy. Maternal running behavior was monitored during pregnancy, and body weight, body composition, food intake, energy expenditure, total cage activity, and running wheel activity were measured in the offspring at various ages. U offspring were slightly heavier at birth, but no group differences in body weight or composition were observed at later ages (when mice were caged without access to running wheels). Consistent with our hypothesis, U offspring were more physically active as adults. This effect was observed earlier in female offspring (at sexual maturation). Remarkably, at 300 d of age, U females achieved greater fat loss in response to a 3-wk voluntary exercise program. Our findings show for the first time that maternal physical activity during pregnancy affects the offspring's lifelong propensity for physical activity and may have important implications for combating the worldwide epidemic of physical inactivity and obesity.-Eclarinal, J. D., Zhu, S., Baker, M. S., Piyarathna, D. B., Coarfa, C., Fiorotto, M. L., Waterland, R. A. Maternal exercise during pregnancy promotes physical activity in adult offspring.
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