Evidence map›Paper›PMID 27032698›Full record

ArticlePsychological medicine2016

Trajectories of depressive symptoms after hip fracture.

P Cristancho, E J Lenze, M S Avidan, K S Rawson

Open access · greenAbstract read
In one paragraph

Article in Psychological medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. AIDEBMC geriatrics · 2026
    Trial
  3. Observational
  4. Review
  5. Article
  6. Incidence and Risk Factors for New-onset Depression After Total Shoulder Arthroplasty.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Article
  7. Article
  8. Suicidal Ideation After Hip Fracture in Older Adults.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Perspectives of patients with depression and chronic pain about bone health after a fragility fracture: A qualitative study.Health expectations : an international journal of public participation in health care and health policy · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

P CristanchoDepartment of Psychiatry,Healthy Mind Lab,Washington University School of Medicine,St Louis,MO,USA.
E J LenzeDepartment of Psychiatry,Healthy Mind Lab,Washington University School of Medicine,St Louis,MO,USA.
M S AvidanDepartment of Anesthesiology,Washington University School of Medicine,St Louis,MO,USA.
K S RawsonDepartment of Psychiatry,Healthy Mind Lab,Washington University School of Medicine,St Louis,MO,USA.
Washington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Training in the Genetics and Molecular Biology of Mental DisordersT32MH014677 · NIMH · WASHINGTON UNIVERSITY · PI RICE, JOHN P. · 1985 to 2020
$3.6M
Risk Genes for Late-Life Depression after Hip FractureR01MH074596 · NIMH · WASHINGTON UNIVERSITY · PI LENZE, ERIC J · 2007 to 2011
$1.9M
2/3 BUPRENORPHINE FOR TREATMENT-RESISTANT LATE-LIFE DEPRESSIONR34MH101433 · NIMH · WASHINGTON UNIVERSITY · PI LENZE, ERIC J · 2014 to 2016
$1.0M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1TR000448NIMH NIH HHS R01 MH074596NIMH NIH HHS R34 MH101433NIMH NIH HHS R34MH101433NIMH NIH HHS T32 MH014677NIMH NIH HHS T32MH014677-36
6 · The paper itself

Abstract

backgroundHip fracture is often complicated by depressive symptoms in older adults. We sought to characterize trajectories of depressive symptoms arising after hip fracture and examine their relationship with functional outcomes and walking ability. We also investigated clinical and psychosocial predictors of these trajectories.

methodWe enrolled 482 inpatients, aged ⩾60 years, who were admitted for hip fracture repair at eight St Louis, MO area hospitals between 2008 and 2012. Participants with current depression diagnosis and/or notable cognitive impairment were excluded. Depressive symptoms and functional recovery were assessed with the Montgomery-Asberg Depression Rating Scale and Functional Recovery Score, respectively, for 52 weeks after fracture. Health, cognitive, and psychosocial variables were gathered at baseline. We modeled depressive symptoms using group-based trajectory analysis and subsequently identified correlates of trajectory group membership.

resultsThree trajectories emerged according to the course of depressive symptoms, which we termed 'resilient', 'distressed', and 'depressed'. The depressed trajectory (10% of participants) experienced a persistently high level of depressive symptoms and a slower time to recover mobility than the other trajectory groups. Stressful life events prior to the fracture, current smoking, higher anxiety, less social support, antidepressant use, past depression, and type of implant predicted membership of the depressed trajectory.

conclusionsDepressive symptoms arising after hip fracture are associated with poorer functional status. Clinical and psychosocial variables predicted membership of the depression trajectory. Early identification and intervention of patients in a depressive trajectory may improve functional outcomes after hip fracture.

Indexed as

Mobility LimitationResilience, PsychologicalAgedAged, 80 and overDepressionFemaleFollow-Up StudiesHip FracturesHumansMaleMiddle AgedMissouriRecovery of FunctionDepressionfunctional recoveryhip fracturemobilityolder adultstrajectory

Identifiers

PMID27032698
PMCPMC4871603
OpenAlexW2259308793

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.