Evidence map›Paper›PMID 27032616›Full record

ReviewTrends in cell biology2016

Signaling by Cellular Protrusions: Keeping the Conversation Private.

Michael Buszczak, Mayu Inaba, Yukiko M Yamashita

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Intrinsic and Microenvironmental Drivers of Glioblastoma Invasion.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Review
  8. Microbiology spectrum · 2022
    Article
  9. Article
  10. Review
  11. Removal of cellular protrusions.Seminars in cell & developmental biology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Mitochondrial Transfer in Cancer: A Comprehensive Review.International journal of molecular sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael BuszczakDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA. Electronic address: michael.buszczak@utsouthwestern.edu.
Mayu InabaDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA; Life Sciences Institute, Department of Cell and Developmental Biology Medical School, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Yukiko M YamashitaLife Sciences Institute, Department of Cell and Developmental Biology Medical School, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: yukikomy@umich.edu.

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Sandi Leigh Pruitt · 2010 to 2026
$53.7M
Systematic Characterization of an Aging Stem Cell NicheR01AG047318 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI BUSZCZAK, MICHAEL · 2015 to 2019
$1.7M
Howard Hughes Medical InstituteNCI NIH HHS P30 CA142543NIA NIH HHS R01 AG047318
6 · The paper itself

Abstract

Information exchange between different cells makes multicellular life possible. Signaling between cells can occur over long distances, as in the case of hormone signaling, or it can take place over short distances between immediately juxtaposed neighbors, as in the case of stem cell-niche signaling. The ability of signal-sending and -receiving cells to communicate with one another in a specific manner is of paramount importance in the proper development and function of tissues. Growing evidence indicates that different cellular protrusions help to achieve specificity in signaling that occurs between distinct cell types. Here, we focus on new roles for cellular protrusions in cell-to-cell communication, drawing special attention to how stem cells use specialized extensions to promote reception of self-renewing signals emanating from the niche.

Indexed as

Signal TransductionAnimalsCell Surface ExtensionsCiliaHumansMicrotubulesNanotubesStem Cellsasymmetric stem cell divisioncytonemesnanotubesstem cell niche

Identifiers

PMID27032616
PMCPMC4914460

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.