ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2018
Survival Advantage Mechanism: Inflammation as a Mediator of Positive Self-Perceptions of Aging on Longevity.
Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Longitudinal effects of subjective aging on health and longevity: An updated meta-analysis.Psychology and aging · 2023Pooled it
- Pooled it
- Positive Self-Perception of Aging and Quality of Life in People Living with HIV: The Role of Cultural Stereotype Internalization.Healthcare (Basel, Switzerland) · 2026Article
- Interaction between perceived ageism and poor sleep quality on frailty among community-dwelling older adults: a cross-sectional study.BMC geriatrics · 2026Article
- Ageism in suicide rates: any difference between Anglo-Saxon and Latin countries?Aging clinical and experimental research · 2026Review
- Aging, Cognition, and Depression: Unraveling the Psychological Pathways of Self-Perceptions of Aging.Psychology research and behavior management · 2026Article
- Roles of benefit finding in psychological and inflammatory adjustments in persons with colorectal cancer: a prospective analysis on the multidimensionality of benefit finding.Psychology & health · 2025Article
- Self-perceptions of aging and sarcopenia in older adults: the mediating role of IADL.Frontiers in medicine · 2025Article
- Self-perceptions of aging and memory in later life: the social pathways.Innovation in aging · 2025Article
- A cohort study of self-perception of ageing and all-cause mortality among older adults in China: a multiple mediators analysis.BMC public health · 2024Article
- The effect of alexithymia on self-perceived aging among community-dwelling older adults with multiple chronic conditions: the mediating role of maladaptive cognitive emotion regulation strategies.Frontiers in psychiatry · 2024Article
- What do we really know about age-related stereotypes and well-being of older adults? A commentary on the state of the art.Frontiers in psychology · 2024Review
- The Relationship between Subjective Aging and Cognition in Elderly People: A Systematic Review.Healthcare (Basel, Switzerland) · 2023Review
- Subjective Aging and Objectively Assessed Hearing Function: A Prospective Study of Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- C-Reactive Protein, Subjective Aging, and Incident Cardiovascular Disease: A Mediation Model.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Effects of physical and mental health factors and family function on the self-perception of aging in the elderly of Chinese community.Brain and behavior · 2022Article
- Broadening the View of Workplace Ageism.Work, aging and retirement · 2022Article
- Associations Between Satisfaction With Aging and Health and Well-being Outcomes Among Older US Adults.JAMA network open · 2022Article
- Neuropsychiatric Disorders and Frailty in Older Adults over the Spectrum of Cancer: A Narrative Review.Cancers · 2022Review
- Positive Self-Perceptions of Aging Play a Significant Role in Predicting Physical Performance among Community-Dwelling Older Adults.International journal of environmental research and public health · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Objective: Previous studies have found that positive self-perceptions of aging (SPA) are associated with longer survival; however, a biological mechanism was unknown. We examined whether C-reactive protein (CRP), a marker of cumulative stress-related inflammation, mediates the relationship between SPA and survival. Method: The SPA of participants aged 50 and older in the Health and Retirement Study (N = 4,149) were assessed at baseline. Inflammation was measured by the level of CRP 4 years later. Survival was followed for up to 6 years. Results: As hypothesized, CRP mediated the impact of SPA on survival. Following the steps of a mediation analysis, positive SPA at baseline predicted lower CRP after 4 years (β = -.29, p = .03) and longer survival in the 2 years following the CRP measurement (β = .20, p =.003); additionally, lower CRP predicted longer survival, after adjusting for positive SPA (β = -.02, p = .0001). All models adjusted for baseline age, CRP, health, sex, race, and education. Discussion: It was found that lower CRP partially mediates the relationship between positive SPA and longer survival. Hence, this study presents a novel pathway to explain the process by which positive SPA extend longevity.
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