SynthesisMedicina oral, patologia oral y cirugia bucal2016
Rapid maxillary expansion and obstructive sleep apnea: A review and meta-analysis.
Synthesis in Medicina oral, patologia oral y cirugia bucal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02805764 (Changes in Upper Airway Anatomy, Quality of Life Measures, and Polysomnographic Parameters Using A Functional Dental Appliance), which is not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes in Upper Airway Anatomy, Quality of Life Measures, and Polysomnographic Parameters Using A Functional Dental Appliance
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Upper airway dimensions in pediatric obstructive sleep-disordered breathing: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Effects of rapid maxillary expansion and functional orthodontic treatment in children with sleep disordered breathing: a systematic review.BMC oral health · 2025Pooled it
- Dental Appliances for the Treatment of Obstructive Sleep Apnea in Children: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Mini-implant assisted rapid palatal expansion (MARPE) effects on adult obstructive sleep apnea (OSA) and quality of life: a multi-center prospective controlled trial.Progress in orthodontics · 2022Trial
- A clinical trial on 3D CT scan and polysomnographyc changes after rapid maxillary expansion in children with snoring.Brazilian journal of otorhinolaryngologyTrial
- Maxillary Arch Expansion and Adenotonsillectomy in Prepubertal Children Diagnosed with Paediatric Obstructive Sleep Apnoea: An Interventional Study.Journal of clinical medicine · 2026Article
- The Role of Craniofacial Abnormalities and Orthodontic Interventions in Residual Obstructive Sleep Apnea after Adenotonsillectomy in Children: A Scoping Review.Medical journal of the Islamic Republic of Iran · 2026Review
- Management of obstructive sleep apnea-hypopnea syndrome in children: what is the role of orthodontics? A scoping review.Sleep & breathing = Schlaf & Atmung · 2025Article
- Rapid maxillary expansion and its impact on sleep apnea in children aged 5 to 8 years: a retrospective study.Dental press journal of orthodontics · 2025Article
- A narrative review on obstructive sleep apnoea syndrome in paediatric population.Frontiers in neurology · 2024Review
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Effects of Rapid Maxillary Expander and Delaire Mask Treatment on Airway Sagittal Dimensions in Pediatric Patients Affected by Class III Malocclusion and Obstructive Sleep Apnea Syndrome.Life (Basel, Switzerland) · 2023Article
- Early Childhood Caries and Sleep Disorders.Journal of clinical medicine · 2023Article
- Effects of Rapid Palatal Expansion on the Upper Airway Space in Children with Obstructive Sleep Apnea (OSA): A Case-Control Study.Children (Basel, Switzerland) · 2023Article
- Oromaxillofacial Surgery: Both a Treatment and a Possible Cause of Obstructive Sleep Apnea-A Narrative Review.Life (Basel, Switzerland) · 2023Review
- Impact of rapid palatal expansion on the size of adenoids and tonsils in children.Sleep medicine · 2022Article
- International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia.Nature reviews. Endocrinology · 2022Review
- The Ogival Palate: A New Risk Marker of Sudden Unexpected Death in Infancy?Frontiers in pediatrics · 2022Article
- The role of the dentist in the diagnosis and management of pediatric obstructive sleep apnea.The Saudi dental journal · 2021Review
- Cone beam computed tomographic evaluation of the changes in condylar position in growing patients with unilateral posterior crossbite undergoing rapid maxillary expansion followed by fixed orthodontic therapy.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOSAS during childhood leads to significant physical and neuropsychomotor impairment. Thus, it needs to be recognized and treated early in order to avoid or attenuate the chronic problems associated with OSAS, which are deleterious to a child's development. Adenotonsillectomy and, in select cases, continuous positive airwaypressure (CPAP) have been the preferred treatments for OSAS in children, and yet they are ineffective at fully ameliorating the disease. Minimally invasive treatments have recently been proposed, comprising intra-oral and extra-oral devices as well as speech therapy. Objetive: to conduct a meta-analysis on studies from around the world that used rapid maxillary expansion (RME) to treat OSAS in children. MATERIAL AND
methodsWe performed a meta-analysis of studies using RME for OSA treatment in children. A literature survey was conductedusing PubMed and Medline for English articles published up to December 2014 with the following descriptors: SleepApnea, Obstructive, Children, Treatment, Orthodontic, Othopaedic, Maxillaryexpansion. Studies were included in the meta-analysisif they were case-controlled studies, randomized, and involved non-syndromic children aged 0 to 12years old diagnosed with OSA by the polysomnography apnea-hypopnea index (AHI) before and after the intervention, submitted RME only.
resultsIn all, 10 articles conformed to the inclusion criteria and were included in this meta-analysis. The total sample size across all these articles was 215 children, having a mean age of 6.7 years,of whom58.6%were male. The mean AHI during the follow-up was -6.86 (p <0.0001).
conclusionsWe concluded that rapid maxillary expansion (RME) in children with OSAS appears to be an effective treatment for this syndrome. Further randomized clinical studies are needed to determine the effectiveness of RME in adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.