ArticleJournal of abnormal psychology2016
Visual integration dysfunction in schizophrenia arises by the first psychotic episode and worsens with illness duration.
Article in Journal of abnormal psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations between psychosis and visual acuity impairment: A systematic review and meta-analysis.Acta psychiatrica Scandinavica · 2021Pooled it
- Virtual reality intervention for visual perception in schizophrenia-a single blind pilot randomized controlled trial.BMC psychiatry · 2025Trial
- The link between basic visual processing and higher-level social cognition: Eye gaze perception as a bridge in a transdiagnostic sample enriched with social dysfunction.Psychological medicine · 2026Article
- Impaired Contour Object Perception in Psychosis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Semantic locality-aware biclustering for brain functional network connectivity.Scientific reports · 2025Article
- Visual integration deficits associated with psychosis are independent of diagnosis.Schizophrenia (Heidelberg, Germany) · 2025Article
- Examining the joint and unique contributions of contour integration and visuospatial memory to altered eye gaze perception in schizophrenia.Schizophrenia research · 2025Article
- Impaired contour object perception in psychosis.medRxiv : the preprint server for health sciences · 2024Article
- Faster bi-stable visual switching in psychosis.Translational psychiatry · 2024Article
- Article
- Alpha peak frequency affects visual performance beyond temporal resolution.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Perceptual Functioning.Current topics in behavioral neurosciences · 2023Article
- Cognitive [Computational] Neuroscience Test Reliability and Clinical Applications for Serious Mental Illness (CNTRaCS) Consortium: Progress and Future Directions.Current topics in behavioral neurosciences · 2023Article
- Visual system assessment for predicting a transition to psychosis.Translational psychiatry · 2022Review
- Both unmedicated and medicated individuals with schizophrenia show impairments across a wide array of cognitive and reinforcement learning tasks.Psychological medicine · 2022Article
- Disrupted Eye Gaze Perception as a Biobehavioral Marker of Social Dysfunction: An RDoC Investigation.Journal of psychiatry and brain science · 2020Article
- Early Visual Processing Is Associated With Social Cognitive Performance in Recent-Onset Schizophrenia.Frontiers in psychiatry · 2020Article
- Article
- Development and Evaluation of a Visual Remediation Intervention for People with Schizophrenia.Journal of psychiatry and brain science · 2020Article
- Smaller visual arrays are harder to integrate in schizophrenia: Evidence for impaired lateral connections in early vision.Psychiatry research · 2019Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
Visual integration dysfunction characterizes schizophrenia, but prior studies have not yet established whether the problem arises by the first psychotic episode or worsens with illness duration. To investigate the issue, we compared chronic schizophrenia patients (SZs), first episode psychosis patients (FEs), and well-matched healthy controls on a brief but sensitive psychophysical task in which subjects attempted to locate an integrated shape embedded in noise. Task difficulty depended on the number of noise elements co-presented with the shape. For half of the experiment, the entire display was scaled down in size to produce a high spatial frequency (HSF) condition, which has been shown to worsen patient integration deficits. Catch trials-in which the circular target appeared without noise-were also added so as to confirm that subjects were paying adequate attention. We found that controls integrated contours under noisier conditions than FEs, who, in turn, integrated better than SZs. These differences, which were at times large in magnitude (d = 1.7), clearly emerged only for HSF displays. Catch trial accuracy was above 95% for each group and could not explain the foregoing differences. Prolonged illness duration predicted poorer HSF integration across patients, but age had little effect on controls, indicating that the former factor was driving the effect in patients. Taken together, a brief psychophysical task efficiently demonstrates large visual integration impairments in schizophrenia. The deficit arises by the first psychotic episode, worsens with illness duration, and may serve as a biomarker of illness progression. (PsycINFO Database Record
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.