ReviewCurrent opinion in gastroenterology2016
Functional lumen imaging probe: The FLIP side of esophageal disease.
Review in Current opinion in gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- FLIP use in achalasia: comparing POEM and Heller myotomy outcomes: a systematic review and meta-analysis.Surgical endoscopy · 2025Pooled it
- Use of the Functional Lumen Imaging Probe in Clinical Esophagology.The American journal of gastroenterology · 2020Guideline
- Pooled it
- Use of intraoperative distensibility index with EndoFLIP™ is independently associated with hiatal hernia recurrence after fundoplication.Surgical endoscopy · 2026Article
- Functional Lumen Imaging Probe (EndoFLIP) in Upper Gastrointestinal Disorders: Current Evidence, Clinical Applications, and Future Perspectives.Diseases (Basel, Switzerland) · 2026Review
- The Role of Functional Lumen Imaging Probe (FLIP) in Addition to High-Resolution Manometry and Timed Barium Esophagram in Treated Achalasia Patients With Persistent or Recurrent Symptoms.Neurogastroenterology and motility · 2026Observational
- Investigating the utility of EndoFLIP™ as a screening tool for pathologic reflux EndoFLIP™ as a screening tool for GERD.Surgical endoscopy · 2026Article
- Sleeve Gastrectomy Leads to Immediate, Significant Intraoperative Increase in Lower Esophageal Distensibility and Opening Area.Journal of clinical medicine · 2026Article
- Gastrointestinal endoscopy for physiological assessment in functional gastrointestinal disorders: a perspective.Frontiers in medicine · 2026Article
- Subjective Assessment of the Pyloric Sphincter During Endoscopy and Its Correlation with FLIP Panometry.Digestive diseases and sciences · 2025Article
- A Software Framework for the Functional Lumen Imaging Probe-Mechanics (MechView).Neurogastroenterology and motility · 2025Article
- Endoscopic impedance planimetry versus high-resolution manometry (HRM) for pre-operative motility evaluation in anti-reflux surgery.Surgical endoscopy · 2024Article
- Modern Achalasia: Diagnosis, Classification, and Treatment.Journal of neurogastroenterology and motility · 2023Review
- A novel EndoFLIP marker during hiatal hernia repair is associated with short-term postoperative dysphagia.Surgical endoscopy · 2022Article
- Nasal trumpet harmoniously improves tolerance to high-resolution impedance manometry catheter placement.Neurogastroenterology and motility · 2022Article
- Use of the functional luminal imaging probe in pediatrics: A comparison study of patients with achalasia before and after endoscopic dilation and non-achalasia controls.Neurogastroenterology and motility · 2021Article
- Comparison of preoperative, intraoperative, and follow-up functional luminal imaging probe measurements in patients undergoing myotomy for achalasia.Gastrointestinal endoscopy · 2021Article
- Intraoperative FLIP distensibility during POEM varies according to achalasia subtype.Surgical endoscopy · 2021Article
- Intraoperative use of FLIP is associated with clinical success following POEM for achalasia.Surgical endoscopy · 2021Article
- Experience-based expert consensus on the intra-operative usage of the Endoflip impedance planimetry system.Surgical endoscopy · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
purpose of reviewThe aim of this review is to summarize use of the functional lumen imaging probe (FLIP) for the evaluation and management of esophageal diseases. RECENT
findingsThe FLIP utilizes high-resolution impedance planimetry to evaluate the functional geometry and cross-sectional area/pressure relationship (i.e. distensibility) of the esophageal sphincters and body. Recent studies have reported the potential utility of FLIP to evaluate esophageal diseases, such as achalasia, gastroesophageal reflux disease, and eosinophilic esophagitis. SUMMARY: Esophageal distensibility measures provided by the FLIP will add to our understanding of the contribution of esophageal mechanical properties to esophageal symptoms and function. Application of the FLIP in clinical practice complements the diagnostic evaluation of esophageal function and may also be a valuable tool to help direct and target clinical management of esophageal diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.