Evidence map›Paper›PMID 27030804›Full record

ArticleMolecular autism2016

Commentary on "Platelet Studies in Autism Spectrum Disorder Patients and First-Degree Relatives".

George M Anderson, Edwin H Cook

Abstract readComment
In one paragraph

Article in Molecular autism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

George M AndersonYale Child Study Center, Yale University School of Medicine, 230 South Frontage Rd., 06519 New Haven, CT USA ; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT USA.
Edwin H CookInstitute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We comment on the recent report entitled "Platelet Studies in Autism Spectrum Disorder Patients and First-Degree Relatives" [Molecular Autism 2015;6:57]. We find it commendable that the authors have investigated platelet factors potentially involved in the well-replicated observation of platelet hyperserotonemia in autism. However, we believe the results need a fuller discussion in the context of prior studies, think that certain aspects of the interpretation need to be reassessed, and attempt to provide a framework for further research in this area.

Indexed as

5-HTAutismHyperserotonemiaPlatelet aggregationPlatelet countPlatelet functioningPlatelet releaseSerotonin

Identifiers

PMID27030804
PMCPMC4812610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.