Evidence map›Paper›PMID 27030788›Full record

ArticleJournal of proteomics & bioinformatics2011

Gene Expression Profiling of Gastric Cancer.

Arivusudar Marimuthu, Harrys K C Jacob, Aniruddha Jakharia, Yashwanth Subbannayya, Shivakumar Keerthikumar, Manoj Kumar Kashyap, Renu Goel, Lavanya Balakrishnan, Sutopa Dwivedi, Swapnali Pathare and 14 more

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PubMed Full text at PMC
In one paragraph

Article in Journal of proteomics & bioinformatics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Identification of Key Transcription Factors Associated with Lung Squamous Cell Carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 1 institution in 1 country.

Arivusudar MarimuthuInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Manipal University, Madhav Nagar, Manipal, Karnataka 576104; India.
Harrys K C JacobInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Manipal University, Madhav Nagar, Manipal, Karnataka 576104; India; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA.
Aniruddha JakhariaDepartment of Zoology, Gauhati University, Guwahati 781014, Assam, India; Imgenex India, Bhubaneswar 751024, Orissa, India.
Yashwanth SubbannayyaInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Rajiv Gandhi University of Health Sciences, Bangalore, 560041, Karnataka, India.
Shivakumar KeerthikumarInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India.
Manoj Kumar KashyapInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Department of Biotechnology, Kuvempu University, Shimoga 577451, Karnataka, India.
Renu GoelInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Department of Biotechnology, Kuvempu University, Shimoga 577451, Karnataka, India.
Lavanya BalakrishnanInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Department of Biotechnology, Kuvempu University, Shimoga 577451, Karnataka, India.
Sutopa DwivediInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; School of Biotechnology, Amrita Vishwa Vidyapeetham University, Kollam 690525, Kerala, India.
Swapnali PathareStrand Life Sciences, Bangalore 560024, Karnataka, India.
Jyoti Bajpai DikshitStrand Life Sciences, Bangalore 560024, Karnataka, India.
Jagadeesha MaharudraiahInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; RajaRajeswari Medical college, Bangalore, 560074, India.
Sujay SinghImgenex India, Bhubaneswar 751024, Orissa, India; Imgenex Corporation, San Diego 92121, California, USA.
Ghantasala S Sameer KumarInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Department of Biotechnology, Kuvempu University, Shimoga 577451, Karnataka, India.
M VijayakumarDepartments of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bangalore 560029, Karnataka; India.
Kariyanakatte Veeraiah Veerendra KumarDepartments of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bangalore 560029, Karnataka; India.
Chennagiri Shrinivasamurthy PremalathaDepartment of Pathology, Kidwai Memorial Institute of Oncology, Bangalore 560029, Karnataka; India.
Pramila TataStrand Life Sciences, Bangalore 560024, Karnataka, India.
Ramesh HariharanStrand Life Sciences, Bangalore 560024, Karnataka, India.
Juan Carlos RoaDepartment of Pathology, Universidad de La Frontera, Temuco, Chile.
T S K PrasadInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Manipal University, Madhav Nagar, Manipal, Karnataka 576104; India.
Raghothama ChaerkadyInstitute of Bioinformatics, International Technology Park, Bangalore, 560066, India; Manipal University, Madhav Nagar, Manipal, Karnataka 576104; India; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA.
Rekha Vijay KumarDepartment of Pathology, Kidwai Memorial Institute of Oncology, Bangalore 560029, Karnataka; India.
Akhilesh PandeyMcKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA.
Manipal Academy of Higher Education · IN

Funding

Tumor Antigens for Individual Signatures and TherapyP50CA062924 · NCI · JOHNS HOPKINS UNIVERSITY · PI LENNON, ANNE MARIE · 1993 to 2022
$54.6M
TCP5: ACTIVE SITE LABELING REAGENT FOR ACETYLTRANSFERASESU54RR020839 · NCRR · JOHNS HOPKINS UNIVERSITY · PI BOEKE, JEF D · 2004 to 2011
$27.4M
NCI NIH HHS P50 CA062924NCRR NIH HHS U54 RR020839
6 · The paper itself

Abstract

Gastric cancer is the second leading cause of cancer death worldwide, both in men and women. A genomewide gene expression analysis was carried out to identify differentially expressed genes in gastric adenocarcinoma tissues as compared to adjacent normal tissues. We used Agilent's whole human genome oligonucleotide microarray platform representing ~41,000 genes to carry out gene expression analysis. Two-color microarray analysis was employed to directly compare the expression of genes between tumor and normal tissues. Through this approach, we identified several previously known candidate genes along with a number of novel candidate genes in gastric cancer. Testican-1 (

Indexed as

DNA microarrayGastric cancerGeneSpring GXImmunohistochemistry

Identifiers

PMID27030788
PMCPMC4809432
OpenAlexW2155516395

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.