ArticleJournal of neurophysiology2016
Receptive field size, chemical and thermal responses, and fiber conduction velocity of rat chorda tympani geniculate ganglion neurons.
Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Article
- Trigeminal innervation and tactile responses in mouse tongue.Cell reports · 2024Article
- Separation of Oral Cooling and Warming Requires TRPM8.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Reduced menthol sensitivity in a prodromal Parkinson's disease model induced by intranasal rotenone treatment.Frontiers in cellular neuroscience · 2024Article
- Anterior and Posterior Tongue Regions and Taste Papillae: Distinct Roles and Regulatory Mechanisms with an Emphasis on Hedgehog Signaling and Antagonism.International journal of molecular sciences · 2023Review
- Oral thermal processing in the gustatory cortex of awake mice.Chemical senses · 2023Article
- Advances in Optical Tools to Study Taste Sensation.Molecules and cells · 2022Review
- Variable Branching Characteristics of Peripheral Taste Neurons Indicates Differential Convergence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Tasting temperature: neural and behavioral responses to thermal stimulation of oral mucosa.Current opinion in physiology · 2021Article
- The Fungiform Papilla Is a Complex, Multimodal, Oral Sensory Organ.Current opinion in physiology · 2021Article
- Cell non-autonomous requirement of p75 in the development of geniculate oral sensory neurons.Scientific reports · 2020Article
- Oral thermosensing by murine trigeminal neurons: modulation by capsaicin, menthol and mustard oil.The Journal of physiology · 2019Article
- TrkB expression and dependence divides gustatory neurons into three subpopulations.Neural development · 2019Article
- Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- The transcription factor Phox2b distinguishes between oral and non-oral sensory neurons in the geniculate ganglion.The Journal of comparative neurology · 2017Article
- Transcriptomes and neurotransmitter profiles of classes of gustatory and somatosensory neurons in the geniculate ganglion.Nature communications · 2017Article
- Modulation of taste processing by temperature.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Review
- Article
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2 authors at 1 institution in 1 country.
Funding
Abstract
Afferent chorda tympani (CT) fibers innervating taste and somatosensory receptors in fungiform papillae have neuron cell bodies in the geniculate ganglion (GG). The GG/CT fibers branch in the tongue to innervate taste buds in several fungiform papillae. To investigate receptive field characteristics of GG/CT neurons, we recorded extracellular responses from GG cells to application of chemical and thermal stimuli. Receptive field size was mapped by electrical stimulation of individual fungiform papillae. Response latency to electrical stimulation was used to determine fiber conduction velocity. Responses of GG neurons to lingual application of stimuli representing four taste qualities, and water at 4°C, were used to classify neuron response properties. Neurons classified as SALT, responding only to NaCl and NH4Cl, had a mean receptive field size of six papillae. Neurons classified as OTHER responded to salts and other chemical stimuli and had smaller mean receptive fields of four papillae. Neurons that responded to salts and cold stimuli, classified as SALT/THERMAL, and neurons responding to salts, other chemical stimuli and cold, classified as OTHER/THERMAL, had mean receptive field sizes of six and five papillae, respectively. Neurons responding only to cold stimuli, categorized as THERMAL, had receptive fields of one to two papillae located at the tongue tip. Based on conduction velocity most of the neurons were classified as C fibers. Neurons with large receptive fields had higher conduction velocities than neurons with small receptive fields. These results demonstrate that GG neurons can be distinguished by receptive field size, response properties and afferent fiber conduction velocity derived from convergent input of multiple taste organs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.