ArticleParasites & vectors2016
Onchocerciasis, an undiagnosed disease in Mozambique: identifying research opportunities.
Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Onchocerciasis overview: pathogenesis, clinical spectrum, and therapeutic challenges of a neglected tropical disease.Frontiers in parasitology · 2026Review
- Cysticercosis and neurocysticercosis in people from Mocuba district, Zambézia province: A Mozambican community-based study.PLoS neglected tropical diseases · 2025Article
- Zambia: A Narrative Review of Success and Challenges in Lymphatic Filariasis Elimination.Tropical medicine and infectious disease · 2024Review
- The burden of T. solium cysticercosis and selected neuropsychiatric disorders in Mocuba district, Zambézia province, Mozambique.PLoS neglected tropical diseases · 2022Article
- Immunoinformatics Design and Assessment of a Multiepitope Antigen (OvMCBL02) for Onchocerciasis Diagnosis and Monitoring.Diagnostics (Basel, Switzerland) · 2022Article
- Disability and its determinants among individuals with onchocerciasis in Southeast Nigeria: a cross-sectional study.The Pan African medical journal · 2022Article
- Neurocysticercosis in Epileptic Children: An Overlooked Condition in Mozambique, Challenges in Diagnosis, Management and Research Priorities.EC microbiology · 2021Article
- Design and Implementation of Postgraduate Programs in Health in a Resource-Limited Setting in Mozambique (The Lúrio University).Advances in medical education and practice · 2021Article
- Assessment of Parasitic Contamination of Lettuce and Cabbages Sold in Selected Markets in Maputo City, Mozambique.EC microbiology · 2021Article
- Prevalence of onchocerciasis and associated clinical manifestations in selected hypoendemic communities in Ghana following long-term administration of ivermectin.BMC infectious diseases · 2019Article
- Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.EC microbiology · 2019Article
- The Search for an Efficient Black Fly Trap for Xenomonitoring of Onchocerciasis.Journal of parasitology research · 2018Review
- Evidence for Suppression of Onchocerciasis Transmission in Bioko Island, Equatorial Guinea.PLoS neglected tropical diseases · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
Abstract
backgroundThe objective of this paper is to summarise and critically review the available data about onchocerciasis in Mozambique, in order to report epidemiological and clinical aspects related to the disease and identify gaps in knowledge. The paper is intended to raise awareness of the existence and importance of this disease and to define research priorities.
methodsWe examined the scarce epidemiological data at our disposal: two diagnostic studies in 1997 and 1998 (first reports on the existence of onchocerciasis in Mozambique), and two Rapid Epidemiological Mapping of Onchocerciasis (REMO) surveys in 2001 and 2007. We examined differences in study designs and methodologies as well as the differing geographical locations to explain the divergence in findings among the studies.
resultsEvidence indicates that onchocerciasis is hypoendemic in Mozambique (with national and imported cases), but still largely remains an undiagnosed illness. There is no awareness of the clinical aspects of the disease and nor of the differential diagnosis with lepromatous leprosy and dermatitis caused by Scabies spp. The use of skin biopsy and a symptom screening questionnaire, combined with nodule rate, in the first two studies may have captured even atypical or subacute presentations. Both REMO surveys relied solely on nodule detection and in the six years between the two studies, the prevalence of nodules detected more than doubled.
conclusionsThe epidemiology and clinical aspects of the disease are unknown in Mozambique. Since the last REMO took place in 2007 and since the population is subject to large-scale movement and displacement, it is important to develop tools to identify and analyse populations that are at high risk for onchocerciasis. Cases of onchocerciasis may be misdiagnosed as leprosy or scabies that fail to improve despite being subjected to treatment against leprosy. Techniques to enable a differential diagnosis need to be established by training health professionals on the recognition of this undiagnosed disease. It is equally necessary to identify the blackfly vectors and where they breed.
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