Evidence map›Paper›PMID 27030114›Full record

SynthesisAmerican journal of men's health2018

Association Between Periodontal Disease and Erectile Dysfunction: A Systematic Review.

Sergio Varela Kellesarian, Tammy Varela Kellesarian, Vanessa Ros Malignaggi, Mansour Al-Askar, Alexis Ghanem, Hans Malmstrom, Fawad Javed

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in American journal of men's health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Sexual Dysfunction in Patients with Chronic Non-Genital Physical Disease: An Umbrella Review.International journal of environmental research and public health · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
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  6. Pooled it
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
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  13. Review
  14. Article
  15. Observational
  16. Article
  17. Oral Health and Erectile Dysfunction.Journal of human reproductive sciences
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sergio Varela Kellesarian1 University of Rochester, Rochester, NY, USA.
Tammy Varela Kellesarian2 Barry University, Miami Shores, FL, USA.
Vanessa Ros Malignaggi3 Universidad Santa Maria, Caracas, Venezuela.
Mansour Al-Askar4 King Saud University, Riyadh, Saudi Arabia.
Alexis Ghanem1 University of Rochester, Rochester, NY, USA.
Hans Malmstrom1 University of Rochester, Rochester, NY, USA.
Fawad Javed1 University of Rochester, Rochester, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A limited number of studies have reported an association between erectile dysfunction (ED) and chronic periodontitis (CP). The aim of the present study is to assess the association between CP and ED through a systematic review of published literature. To address the focused question, "Is there a relationship between ED and CP?" indexed databases were searched till December 2015 using various key words "erectile dysfunction," "periodontal disease," "periodontitis," "dental infection," and "impotence." Letters to the editor, commentaries, historic reviews, and experimental studies were excluded. The pattern of the present systematic review was customized to primarily summarize the pertinent data. Nine studies were included. Seven studies had a cross-sectional design and two studies were randomized control trials. The number of study participants ranged between 53 and 513,258 individuals with age ranging between 20 years and 85 years (median age ranging between 34.9 ± 4.9 years and 50.9 ± 16.6 years). In all studies, a positive relationship between CP and ED was reported. In four studies, odds ratio were reported, ranging between 1.53 and 3.35. From the literature reviewed, there seems to be a positive association between ED and CP; however, further well-designed controlled clinical trials are needed in this regard. It is emphasized that physicians should refer patients with ED to oral health care providers for a comprehensive oral evaluation and treatment.

Indexed as

Chronic PeriodontitisErectile DysfunctionAdultAgedAged, 80 and overConfounding Factors, EpidemiologicCross-Sectional StudiesHumansMaleMiddle AgedYoung Adultchronic periodontal diseaseerectile dysfunction

Identifiers

PMID27030114
PMCPMC5818109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.