ReviewAsian journal of andrology
Varicocele management in the era of in vitro fertilization/intracytoplasmic sperm injection.
Review in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Surgical or radiological treatment for varicoceles in subfertile men.The Cochrane database of systematic reviews · 2021Pooled it
- Ultrasound evaluation of varicoceles: systematic literature review and rationale of the ESUR-SPIWG Guidelines and Recommendations.Journal of ultrasound · 2020Pooled it
- Experimental Varicocele Impairs DNA Methylation and Demethylation in Germ Cells, TESE, and Epididymal Spermatozoa, Impacting Active DNA Demethylation in Zygotes.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Seminal Calbindin 2 in Infertile Men With Varicocele: A Prospective Comparative Study.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota.Journal of clinical medicine · 2023Review
- A Novel Approach to Improving the Reliability of Manual Semen Analysis: A Paradigm Shift in the Workup of Infertile Men.The world journal of men's health · 2021Review
- Comparison of outcomes in intrauterine insemination,International journal of medical sciences · 2020Article
- Left spermatic vein reflux after varicocele repair predicts pregnancies and live births in subfertile couples.Journal of endocrinological investigation · 2019Observational
- Treating varicocele in 2018: current knowledge and treatment options.Journal of endocrinological investigation · 2018Review
- Role of varicocele treatment in assisted reproductive technologies.Arab journal of urology · 2018Review
- Semen parameters in men with varicocele: DNA fragmentation, chromatin packaging, mitochondrial membrane potential, and apoptosis.JBRA assisted reproduction · 2017Article
- Potential role of imaging in assessing harmful effects on spermatogenesis in adult testes with varicocele.World journal of radiology · 2017Review
- Spermatozoal Fractalkine Signaling Pathway Is Upregulated in Subclinical Varicocele Patients with Normal Seminogram and Low-Level Leucospermia.Advances in urology · 2017Article
- An association between sperm PLCζ levels and varicocele?Journal of assisted reproduction and genetics · 2016Article
- Subinguinal microsurgical varicocelectomy is safe and effective in a solitary testicle.Asian journal of andrologyArticle
- Is varicocele repair necessary, given the advanced state of assisted reproductive technologies?Asian journal of andrologyArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Varicocele is the most common surgically treatable cause of male infertility, and often results in alterations in semen parameters, sperm DNA damage, and changes to the seminal milieu. Varicocele repair can result in improvement in these parameters in the majority of men with clinical varicocele; data supporting repair in men with subclinical varicocele are less definitive. In couples seeking fertility using assisted reproductive technologies (ARTs), varicocele repair may offer improvement in semen parameters and sperm health that can increase the likelihood of successful fertilization using techniques such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI), or may decrease the level of ART needed to achieve successful pregnancy. Male infertility is an indicator of general male health, and evaluation of the infertile male with an eye toward future health can facilitate optimal screening and treatment of these men. Furthermore, varicocele may represent a progressive lesion, offering an argument for its repair, although this is currently unclear.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.