ArticleGlia2016
Radial glia inhibit peripheral glial infiltration into the spinal cord at motor exit point transition zones.
Article in Glia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 30 citations in OpenAlex.
- The regenerative period of somatosensory nerves is closed by a DCC signaling axis.PLoS genetics · 2026Article
- Microglia cannibalism and efferocytosis leads to shorter lifespans of developmental microglia.PLoS biology · 2024Article
- Microglia cannibalism and efferocytosis leads to shorter lifespans of developmental microglia.bioRxiv : the preprint server for biology · 2024Article
- Glial plasticity at nervous system transition zones.Biology open · 2023Review
- The embryonic zebrafish brain is seeded by a lymphatic-dependent population of mrc1Nature neuroscience · 2022Article
- A Subset of Oligodendrocyte Lineage Cells Interact With the Developing Dorsal Root Entry Zone During Its Genesis.Frontiers in cellular neuroscience · 2022Article
- Identification of astroglia-like cardiac nexus glia that are critical regulators of cardiac development and function.PLoS biology · 2021 · on this mapArticle
- Transgenic fluorescent zebrafish lines that have revolutionized biomedical research.Laboratory animal research · 2021Review
- Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia.eLife · 2021Article
- Engulfed by Glia: Glial Pruning in Development, Function, and Injury across Species.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Review
- Tetris in the Nervous System: What Principles of Neuronal Tiling Can Tell Us About How Glia Play the Game.Frontiers in cellular neuroscience · 2021Review
- Functional Regeneration of the Sensory Root via Axonal Invasion.Cell reports · 2020Article
- More Than Mortar: Glia as Architects of Nervous System Development and Disease.Frontiers in cell and developmental biology · 2020Review
- Article
- Cell migration and axon guidance at the border between central and peripheral nervous system.Science (New York, N.Y.) · 2019Review
- Pioneer axons employ Cajal's battering ram to enter the spinal cord.Nature communications · 2019Article
- Single-cell Photoconversion in Living Intact Zebrafish.Journal of visualized experiments : JoVE · 2018Article
- Motor Exit Point (MEP) Glia: Novel Myelinating Glia That Bridge CNS and PNS Myelin.Frontiers in cellular neuroscience · 2018Review
- Livin' On The Edge: glia shape nervous system transition zones.Current opinion in neurobiology · 2017Review
- The secreted neurotrophin Spätzle 3 promotes glial morphogenesis and supports neuronal survival and function.Genes & development · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
In the mature vertebrate nervous system, central and peripheral nervous system (CNS and PNS, respectively) GLIA myelinate distinct motor axon domains at the motor exit point transition zone (MEP TZ). How these cells preferentially associate with and myelinate discrete, non-overlapping CNS versus PNS axonal segments, is unknown. Using in vivo imaging and genetic cell ablation in zebrafish, we demonstrate that radial glia restrict migration of PNS glia into the spinal cord during development. Prior to development of radial glial endfeet, peripheral cells freely migrate back and forth across the MEP TZ. However, upon maturation, peripherally located cells never enter the CNS. When we ablate radial glia, peripheral glia ectopically migrate into the spinal cord during developmental stages when they would normally be restricted. These findings demonstrate that radial glia contribute to both CNS and PNS development and control the unidirectional movement of glial cell types across the MEP TZ early in development. GLIA 2016. GLIA 2016;64:1138-1153.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.