ReviewMaternal and child health journal2016
Developmental Origins, Epigenetics, and Equity: Moving Upstream.
Review in Maternal and child health journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic literature review of protective factors mitigating intimate partner violence exposure on early childhood health outcomes.Journal of advanced nursing · 2023Pooled it
- The effects of probiotics supplementation on metabolic health in pregnant women: An evidence based meta-analysis.PloS one · 2018Pooled it
- The Camden Study-A Pregnancy Cohort Study of Pregnancy Complications and Birth Outcomes in Camden, New Jersey, USA.Nutrients · 2024Article
- The Eastern Door Center: re-balancing the wheel-a Two-Eyed Seeing approach to FASD and other disorders related to transgenerational adversity.Frontiers in sociology · 2023Article
- Restoring the missing person to personalized medicine and precision psychiatry.Frontiers in neuroscience · 2023Article
- Framing action to reduce health inequalities: what is argued for through use of the 'upstream-downstream' metaphor?Journal of public health (Oxford, England) · 2022Review
- Maternal resveratrol supplementation ameliorates bisphenol A-induced atherosclerotic lesions formation in adult offspring ApoE3 Biotech · 2022Article
- Editorial: Identifying the Interdisciplinary Determinants, Biologic Mechanisms, and Best Practices for the Prevention and Elimination of Minority Health Disparities.Frontiers in public health · 2022Article
- Parental Educational Attainment, the Superior Temporal Cortical Surface Area, and Reading Ability among American Children: A Test of Marginalization-Related Diminished Returns.Children (Basel, Switzerland) · 2021Article
- Environmental and socio-cultural impacts on global DNA methylation in the indigenous Huichol population of Nayarit, Mexico.Environmental science and pollution research international · 2021Article
- An Examination of History for Promoting Diversity in Neuroscience.Current anesthesiology reports · 2021Review
- Incorporating Measures of Structural Racism into Population Studies of Reproductive Health in the United States: A Narrative Review.Health equity · 2021Review
- Novel pathways of inflammation in human fetal membranes associated with preterm birth and preterm pre-labor rupture of the membranes.Seminars in immunopathology · 2020Review
- Comorbidity patterns and socioeconomic inequalities in children under 15 with medical complexity: a population-based study.BMC pediatrics · 2020Article
- Nutrition Disparities and Cardiovascular Health.Current atherosclerosis reports · 2020Review
- High-fat diet from parental generation exaggerates body and adipose tissue weights in pregnant offspring.PloS one · 2020Article
- Epigenetics, ethics, law and society: A multidisciplinary review of descriptive, instrumental, dialectical and reflexive analyses.Social studies of science · 2019Review
- Analyzing Policies Through a DOHaD Lens: What Can We Learn?International journal of environmental research and public health · 2018Article
- An Intergenerational Approach to Break the Cycle of Malnutrition.Current nutrition reports · 2018Review
- Postnatal screening and care for non-medical risk factors by preventive child healthcare in deprived and non-deprived neighbourhoods.BMC health services research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Developmental Origins of Health and Disease and the related science of epigenetics redefines the meaning of what constitutes upstream approaches to significant social and public health problems. An increasingly frequent concept being expressed is "When it comes to your health, your zip code may be more important than your genetic code". Epigenetics explains how the environment-our zip code-literally gets under our skin, creates biological changes that increase our vulnerability for disease, and even children's prospects for social success, over their life course and into future generations. This science requires us to rethink where disease comes from and the best way to promote health. It identifies the most fundamental social equity issue in our society: that initial social and biological disadvantage, established even prior to birth, and linked to the social experience of prior generations, is made worse by adverse environments throughout the life course. But at the same time, it provides hope because it tells us that a concerted focus on using public policy to improve our social, physical, and economic environments can ultimately change our biology and the trajectory of health and social success into future generations.
Indexed as
Identifiers
27029539What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.