ArticlePediatric rheumatology online journal2016
Henoch-Schönlein purpura with joint involvement: Analysis of 71 cases.
Article in Pediatric rheumatology online journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk prediction models for renal injury in children with IgA vasculitis: a systematic review and meta-analysis.Pediatric rheumatology online journal · 2025Pooled it
- Risk Factors Associated with Renal Involvement in Childhood Henoch-Schönlein Purpura: A Meta-Analysis.PloS one · 2016Pooled it
- Association between immune cells and allergic purpura: a Mendelian randomization study.Italian journal of pediatrics · 2025Article
- Abdominal imaging and endoscopic characteristics of adult abdominal IgA vasculitis: a multicenter retrospective study.Annals of medicine · 2024Article
- Predicting renal damage in children with IgA vasculitis by machine learning.Pediatric nephrology (Berlin, Germany) · 2024Article
- ASSOCIATION BETWEEN HIGH MOBILITY GROUP BOX 1 PROTEIN GENE (rs41369348) POLYMORPHISM AND IMMUNOGLOBULIN A VASCULITIS IN CHILDREN.Acta clinica Croatica · 2023Article
- Reporting the clinical spectrum of children with IgAV in a retrospective 24-year cohort: Influences of age and sex on clinical presentation.Turkish journal of medical sciences · 2023Article
- Clinical characteristics and associating risk factors of gastrointestinal perforation in children with IgA vasculitis.Annals of medicine · 2021Article
- Streptococcal infection in childhood Henoch-Schönlein purpura: a 5-year retrospective study from a single tertiary medical center in China, 2015-2019.Pediatric rheumatology online journal · 2021Article
- Epidemiology and Clinical Characteristics of Henoch-Schönlein Purpura Associated withMediterranean journal of hematology and infectious diseases · 2021Article
- Obesity is associated with severe clinical course in children with Henoch-Schonlein purpura.Pediatric nephrology (Berlin, Germany) · 2020Article
- The clinical spectrum of Henoch-Schönlein purpura in children: a single-center study.Clinical rheumatology · 2019Article
- Childhood IgA Vasculitis (Henoch Schonlein Purpura)-Advances and Knowledge Gaps.Frontiers in pediatrics · 2019Review
- Determination of Risk Factors in Children Diagnosed With Henoch-Schönlein Purpura.Archives of rheumatology · 2018Article
- Article
- Henoch-Schönlein purpura nephritis: initial risk factors and outcomes in a Latin American tertiary center.Clinical rheumatology · 2018Article
- Henoch-Schonlein Purpura in Children Hospitalized at a Tertiary Hospital during 2004-2015 in Korea: Epidemiology and Clinical Management.Pediatric gastroenterology, hepatology & nutrition · 2016Article
- Renal biopsy in children with IgA vasculitis.Jornal brasileiro de nefrologiaArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough joint involvement is the second most common clinical manifestation after skin involvement in patients with Henoch-Schönlein purpura (HSP), it has not been well characterized. The aim of this study was to profile the clinical characteristics and identify the potential risk factors for kidney damage in HSP patients having joint involvement.
methodsWe retrospectively reviewed 71 cases of HSP patients with joint involvement who attended our hospital between January 2010 and March 2012 and analyzed their epidemiological profile, clinical characteristics, follow-up findings (up to three years) and overall prognosis. Logistic regression analysis was performed to identify risk factors associated with renal symptoms in HSP patients with joint involvement.
resultsAverage age of patients was 8.55 ± 2.13 years with male to female ratio at 1.29:1. The peak age of disease onset was six to 11 years. The most common triggers included upper respiratory infection, vigorous physical activity, and autumn and winter seasons. Forty cases (56.35 %) had gastrointestinal involvement and 37 (52.11 %) had kidney damage; gastrointestinal system, scrotal involvement, and increased D-dimer levels were significantly associated with kidney injury (P < 0.05) by multivariate analysis. Glucocorticoid therapy was effective in alleviating symptoms.
conclusionGastrointestinal symptoms, scrotal involvement, and increased D-dimer are the potential risk factors for kidney damage in HSP patients having joint involvement. Rational use of corticosteroids was probably responsible for the good clinical outcomes.
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