ArticleGenetics, selection, evolution : GSE2016
Genetic diversity analysis of two commercial breeds of pigs using genomic and pedigree data.
Article in Genetics, selection, evolution : GSE, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed, 89 citations in OpenAlex.
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- Exploring genomic inbreeding and selection signatures in a commercial Brangus herd through functional annotation.Journal of applied genetics · 2024Article
- Genome-wide analysis of population structure, effective population size and inbreeding in Iranian and exotic horses.PloS one · 2024Article
- Selective Sweeps in the Austrian Turopolje and Other Commercial Pig Populations.Animals : an open access journal from MDPI · 2023Article
- Characterization analysis of Rongchang pig population based on the Zhongxin-1 Porcine Breeding Array PLUS.Animal bioscience · 2023Article
- Genome-Wide Assessment of Runs of Homozygosity by Whole-Genome Sequencing in Diverse Horse Breeds Worldwide.Genes · 2023Article
- The coefficients of inbreeding revealed by ROH study among inbred individuals belonging to each type of the first cousin marriage: A preliminary report from North India.Genes & genomics · 2023Article
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- Genome-wide study of linkage disequilibrium, population structure, and inbreeding in Iranian indigenous sheep breeds.PloS one · 2023Article
- Single nucleotide polymorphism-based analysis of the genetic structure of the Min pig conserved population.Animal bioscience · 2022Article
- Estimate of inbreeding depression on growth and reproductive traits in a Large White pig population.G3 (Bethesda, Md.) · 2022Article
- Genetic diversity and population structure of six autochthonous pig breeds from Croatia, Serbia, and Slovenia.Genetics, selection, evolution : GSE · 2022Article
- Evolutionary pressures rendered by animal husbandry practices for avian influenza viruses to adapt to humans.iScience · 2022Review
- Genetic and phenotypic correlations between backfat thickness and weight at 28 weeks of age, and reproductive performance in primiparous Landrace sows raised under tropical conditions.Tropical animal health and production · 2022Article
- Population genetic structure analysis and identification of backfat thickness loci of Chinese synthetic Yunan pigs.Frontiers in genetics · 2022Article
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Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGenetic improvement in livestock populations can be achieved without significantly affecting genetic diversity if mating systems and selection decisions take genetic relationships among individuals into consideration. The objective of this study was to examine the genetic diversity of two commercial breeds of pigs. Genotypes from 1168 Landrace (LA) and 1094 Large White (LW) animals from a commercial breeding program in Brazil were obtained using the Illumina PorcineSNP60 Beadchip. Inbreeding estimates based on pedigree (F x) and genomic information using runs of homozygosity (F ROH) and the single nucleotide polymorphisms (SNP) by SNP inbreeding coefficient (F SNP) were obtained. Linkage disequilibrium (LD), correlation of linkage phase (r) and effective population size (N e ) were also estimated.
resultsEstimates of inbreeding obtained with pedigree information were lower than those obtained with genomic data in both breeds. We observed that the extent of LD was slightly larger at shorter distances between SNPs in the LW population than in the LA population, which indicates that the LW population was derived from a smaller N e . Estimates of N e based on genomic data were equal to 53 and 40 for the current populations of LA and LW, respectively. The correlation of linkage phase between the two breeds was equal to 0.77 at distances up to 50 kb, which suggests that genome-wide association and selection should be performed within breed. Although selection intensities have been stronger in the LA breed than in the LW breed, levels of genomic and pedigree inbreeding were lower for the LA than for the LW breed.
conclusionsThe use of genomic data to evaluate population diversity in livestock animals can provide new and more precise insights about the effects of intense selection for production traits. Resulting information and knowledge can be used to effectively increase response to selection by appropriately managing the rate of inbreeding, minimizing negative effects of inbreeding depression and therefore maintaining desirable levels of genetic diversity.
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