ReviewActa paediatrica (Oslo, Norway : 1992)2016
Challenges in nourishing the intrauterine growth-restricted foetus - Lessons learned from studies in the intrauterine growth-restricted foetal sheep.
Review in Acta paediatrica (Oslo, Norway : 1992), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Slow-twitch oxidative myofiber proportions and capillary number per myofiber are reduced in growth-restricted fetal sheep.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Article
- Mitochondrial respiration is lower in the intrauterine growth-restricted fetal sheep heart.The Journal of physiology · 2024Article
- Effect of Genetically Reduced Maternal Myostatin on Late Gestation Maternal, Fetal, and Placental Metabolomes in Mice.Metabolites · 2023Article
- Impact of Placental SLC2A3 Deficiency during the First-Half of Gestation.International journal of molecular sciences · 2022Article
- Fetal Sex Does Not Impact Placental Blood Flow or Placental Amino Acid Transfer in Late Gestation Pregnant Sheep With or Without Placental Insufficiency.Reproductive sciences (Thousand Oaks, Calif.) · 2022Article
- Lower citrate synthase activity, mitochondrial complex expression, and fewer oxidative myofibers characterize skeletal muscle from growth-restricted fetal sheep.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Treadmill Running of Mouse as a Model for Studying Influence of Maternal Exercise on Offspring.Bio-protocol · 2020Article
- Effects of birth weight and dietary fat on intake, body composition, and plasma thyroxine in neonatal lambs.Journal of animal science · 2020Article
- Differentially expressed genes in cotyledon of ewes fed mycotoxins.BMC genomics · 2020Article
- Sex Differences Across the Lifespan: A Focus on Cardiometabolism.Journal of women's health (2002) · 2020Article
- Real supermodels wear wool: summarizing the impact of the pregnant sheep as an animal model for adaptive fetal programming.Animal frontiers : the review magazine of animal agriculture · 2019Article
- Prolonged amino acid infusion into intrauterine growth-restricted fetal sheep increases leucine oxidation rates.American journal of physiology. Endocrinology and metabolism · 2018Article
- Atypical fetal development: Fetal alcohol syndrome, nutritional deprivation, teratogens, and risk for neurodevelopmental disorders and psychopathology.Development and psychopathology · 2018Review
- Fetal adaptations in insulin secretion result from high catecholamines during placental insufficiency.The Journal of physiology · 2017Review
- RNA Sequencing Exposes Adaptive and Immune Responses to Intrauterine Growth Restriction in Fetal Sheep Islets.Endocrinology · 2017Article
- Optimizing nutrition of the preterm infant.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- Impact of thermal stress on placental function and fetal physiology.Animal reproductionArticle
- Maternal Lipid Profile as a Risk Factor for Gestational Diabetes Mellitus in Obese Women.Current health sciences journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
unlabelledPrevious attempts to improve growth and development of the intrauterine growth-restricted (IUGR) foetus during pregnancy have not worked or caused harm. Our research identifies tissue-specific mechanisms underlying foetal growth restriction and then tests strategies to improve growth and ameliorate many of the metabolic problems before the infant is born. The goal of our studies is to reduce the impact of foetal growth restriction at critical stages of development on the lifelong complications of IUGR offspring.
conclusionDefining specific mechanisms that cause growth restriction in the foetus might identify specific nutrients and hormones that could be given to the mother to improve foetal growth and reduce metabolic complications, using strategies first tested in our IUGR animal model.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.