Evidence map›Paper›PMID 27028631›Full record

ReviewBiophysical journal2016

A Primer on the Bayesian Approach to High-Density Single-Molecule Trajectories Analysis.

Mohamed El Beheiry, Silvan Türkcan, Maximilian U Richly, Antoine Triller, Antigone Alexandrou, Maxime Dahan, Jean-Baptiste Masson

Abstract readReview
In one paragraph

Review in Biophysical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. DNA replication:Computational and structural biotechnology journal · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed El BeheiryLaboratoire Physico-Chimie, Institut Curie, PSL Research University, Paris, France; Department of Radiation Oncology, Sorbonne Universités, Paris, France; Physics of Biological Systems, Institut Pasteur, Paris, France.
Silvan TürkcanDivision of Medical Physics, Stanford University School of Medicine, Palo Alto, California.
Maximilian U RichlyLaboratoire d'Optique et Biosciences, Ecole Polytechnique, Université Paris-Saclay, Palaiseau, France.
Antoine TrillerBiologie Cellulaire de la Synapse, École Normale Supérieure, PSL Research University, Paris, France.
Antigone AlexandrouLaboratoire d'Optique et Biosciences, Ecole Polytechnique, Université Paris-Saclay, Palaiseau, France.
Maxime DahanLaboratoire Physico-Chimie, Institut Curie, PSL Research University, Paris, France; Department of Radiation Oncology, Sorbonne Universités, Paris, France; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia.
Jean-Baptiste MassonPhysics of Biological Systems, Institut Pasteur, Paris, France; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia. Electronic address: jbmasson@pasteur.fr.

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Tracking single molecules in living cells provides invaluable information on their environment and on the interactions that underlie their motion. New experimental techniques now permit the recording of large amounts of individual trajectories, enabling the implementation of advanced statistical tools for data analysis. In this primer, we present a Bayesian approach toward treating these data, and we discuss how it can be fruitfully employed to infer physical and biochemical parameters from single-molecule trajectories.

Indexed as

Bayes TheoremCarrier ProteinsHeLa CellsHumansLikelihood FunctionsMembrane ProteinsProtein Structure, SecondaryCarrier ProteinsgephyrinMembrane Proteins

Identifiers

PMID27028631
PMCPMC4816684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.