ArticleHIV medicine2016
Fall frequency and associated factors among men and women with or at risk for HIV infection.
Article in HIV medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Developing an HIV-specific falls risk prediction model with a novel clinical index: a systematic review and meta-analysis method.BMC infectious diseases · 2024Pooled it
- Objective impairments of gait and balance in adults living with HIV-1 infection: a systematic review and meta-analysis of observational studies.BMC musculoskeletal disorders · 2017Pooled it
- A Fall Prevention Feasibility Trial for People With HIV and Alcohol Use.OTJR : occupation, participation and health · 2025Trial
- Effect of vitamin DAntiviral therapy · 2020Trial
- Association of Cannabis Use With Risk of Subsequent Falls Among Adults Aging With HIV.Open forum infectious diseases · 2026Article
- Alcohol use disorder, but not current alcohol use is associated with falls among people with HIV in care.AIDS (London, England) · 2025Article
- Alcohol Use and Its Associations With Frailty, Fractures, and Falls Among Older Adults With HIV.Alcohol research : current reviews · 2025Review
- Cardiometabolic health in people with HIV: expert consensus review.The Journal of antimicrobial chemotherapy · 2024Review
- Trends and age-period-cohort effect on the incidence of falls from 1990 to 2019 in BRICS.Heliyon · 2024Article
- Sex Differences in the Prevalence of Geriatric Syndromes Among Older People Living with HIV Attending an Urban Outpatient Clinic in Kampala, Uganda.HIV/AIDS (Auckland, N.Z.) · 2024Article
- Antiretroviral drug use and the risk of falls in people living with HIV: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2023Review
- HIV and an Ageing Population-What Are the Medical, Psychosocial, and Palliative Care Challenges in Healthcare Provisions.Microorganisms · 2023Review
- The Impact of Number of Medications on Falls in Aging Persons with Human Immunodeficiency Virus.Life (Basel, Switzerland) · 2023Article
- Alcohol and falls among people with HIV infection: A view from Russia and the United States.Alcoholism, clinical and experimental research · 2022Article
- Regional Differences in Risk of Recurrent Falls Among Older U.S. Women and Men with HIV in the HIV Infection, Aging, and Immune Function Long-Term Observational Study.AIDS research and human retroviruses · 2022Observational
- Geriatric conditions and healthcare utilisation in older adults living with HIV.Age and ageing · 2022Article
- Low Quality of Life, Falls, and Pre-Frailty are Associated with Depressive Symptoms in Virologically Suppressed PLWHIV in Salvador, Brazil.AIDS and behavior · 2022Article
- Risk of Falls in HIV-Infected Patients on Antiretroviral Therapy and Its Associated Factors.HIV/AIDS (Auckland, N.Z.) · 2022Article
- HIV and Aging: Overcoming Challenges in Existing HIV Guidelines to Provide Patient-Centered Care for Older People with HIV.Pathogens (Basel, Switzerland) · 2021Article
- Health system challenges affecting falls prevention in persons living with HIV: perspectives from physiotherapists in four sub-Saharan regions.Primary health care research & development · 2021Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
objectivesFalls and fall-related injuries are a major public health concern. HIV-infected adults have been shown to have a high incidence of falls. Identification of major risk factors for falls that are unique to HIV infection or similar to those in the general population will inform development of future interventions for fall prevention.
methodsHIV-infected and uninfected men and women participating in the Hearing and Balance Substudy of the Multicenter AIDS Cohort Study and Women's Interagency HIV Study were asked about balance symptoms and falls during the prior 12 months. Falls were categorized as 0, 1, or ≥ 2; proportional odds logistic regression models were used to investigate relationships between falls and demographic and clinical variables and multivariable models were created.
resultsTwenty-four per cent of 303 HIV-infected participants reported at least one fall compared with 18% of 233 HIV-uninfected participants (P = 0.27). HIV-infected participants were demographically different from HIV-uninfected participants, and were more likely to report clinical imbalance symptoms (P ≤ 0.035). In univariate analyses, more falls were associated with hepatitis C, female sex, obesity, smoking, and clinical imbalance symptoms, but not age, HIV serostatus or other comorbidities. In multivariable analyses, female sex and imbalance symptoms were independently associated with more falls. Among HIV-infected participants, smoking, a higher number of medications, and imbalance symptoms remained independent fall predictors, while current protease inhibitor use was protective.
conclusionsSimilar rates of falls among HIV-infected and uninfected participants were largely explained by a high prevalence of imbalance symptoms. Routine assessment of falls and dizziness/imbalance symptoms should be considered, with interventions targeted at reducing symptomatology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.