ArticlePloS one2016
Copper-Containing Anti-Biofilm Nanofiber Scaffolds as a Wound Dressing Material.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Copper Complexes: Emerging Micro- and Nanosystems for Dermatological Treatment.Pharmaceutics · 2026Review
- Article
- Impeding Biofilm-Forming Mediated Methicillin-ResistantBiomolecules · 2025Article
- Nanoparticle-Based Strategies for Managing Biofilm Infections in Wounds: A Comprehensive Review.ACS omega · 2024Review
- Intelligent electrospinning nanofibrous membranes for monitoring and promotion of the wound healing.Materials today. Bio · 2024Review
- Article
- Copper incorporated biomaterial-based technologies for multifunctional wound repair.Theranostics · 2024Review
- Electrospun Nanofiber Scaffolds Loaded with Metal-Based Nanoparticles for Wound Healing.Polymers · 2023Review
- Transforming Wound Management: Nanomaterials and Their Clinical Impact.Pharmaceutics · 2023Review
- Perspectives on Usage of Functional Nanomaterials in Antimicrobial Therapy for Antibiotic-Resistant Bacterial Infections.ACS omega · 2023Review
- Synergistic Antibacterial Activity of Benzalkonium Bromide and Cu-Bearing Duplex Stainless Steel againstMicroorganisms · 2023Article
- The impact of agarose immobilization on the activity of lytic Pseudomonas aeruginosa phages combined with chemicals.Applied microbiology and biotechnology · 2023Article
- Recent advances in copper and copper-derived materials for antimicrobial resistance and infection control.Current opinion in biomedical engineering · 2022Review
- Effectiveness of Copper Nanoparticles in Wound Healing Process Using In Vivo and In Vitro Studies: A Systematic Review.Pharmaceutics · 2022Review
- Fabrication of Ceftriaxone-Loaded Cellulose Acetate and Polyvinyl Alcohol Nanofibers and Their Antibacterial Evaluation.Antibiotics (Basel, Switzerland) · 2022Article
- Review
- Role of copper nanoparticles in wound healing for chronic wounds: literature review.Burns & trauma · 2022Review
- The In Vitro Anti-Pseudomonal Activity of CuInternational journal of molecular sciences · 2021Article
- Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections.Nature reviews. Microbiology · 2021Review
- Copper Surfaces in Biofilm Control.Nanomaterials (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Copper particles were incorporated into nanofibers during the electrospinning of poly-D,L-lactide (PDLLA) and poly(ethylene oxide) (PEO). The ability of the nanofibers to prevent Pseudomonas aeruginosa PA01 and Staphylococcus aureus (strain Xen 30) to form biofilms was tested. Nanofibers containing copper particles (Cu-F) were thinner (326 ± 149 nm in diameter), compared to nanofibers without copper (CF; 445 ± 93 nm in diameter). The crystalline structure of the copper particles in Cu-F was confirmed by X-ray diffraction (XRD). Copper crystals were encapsulated, but also attached to the surface of Cu-F, as shown scanning transmission electron microscopy (STEM) and transmission electron microscopy (TEM), respectively. The copper particles had no effect on the thermal degradation and thermal behaviour of Cu-F, as shown by thermogravimetric analysis (TGA) and differential scanning calorimeter (DSC). After 48 h in the presence of Cu-F, biofilm formation by P. aeruginosa PA01 and S. aureus Xen 30 was reduced by 41% and 50%, respectively. Reduction in biofilm formation was ascribed to copper released from the nanofibers. Copper-containing nanofibers may be incorporated into wound dressings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.